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Clinical Trials/NCT01030107
NCT01030107
Completed
Not Applicable

Sleep Duration and Pediatric Overweight: the Role of Eating Behaviors

The Miriam Hospital1 site in 1 country37 target enrollmentFebruary 2009
ConditionsSleepObesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sleep
Sponsor
The Miriam Hospital
Enrollment
37
Locations
1
Primary Endpoint
absolute reinforcing value of food as compared to sedentary activities
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.

Registry
clinicaltrials.gov
Start Date
February 2009
End Date
January 2012
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 8-11 years old
  • BMI for age and gender \> 5th percentile (but no greater than 100% overweight)
  • Sleep approximately 9-10 hours nightly
  • Attend elementary school
  • Like at least 1 food and 1 activity used in the reinforcement paradigm
  • Able to understand and complete the reinforcement paradigm

Exclusion Criteria

  • Existence of a diagnosable sleep disorder
  • Medical or psychiatric condition that could influence sleep or weight
  • Onset of menarche
  • Inability to complete study materials, including diagnosed disabilities
  • Dietary restrictions/allergies to foods used in the study that preclude them from study participation

Outcomes

Primary Outcomes

absolute reinforcing value of food as compared to sedentary activities

Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration

Secondary Outcomes

  • subjective ratings of hunger and appetite(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • caloric intake(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • plasma levels of leptin and ghrelin(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • levels of physical activity(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)

Study Sites (1)

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