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临床试验/NCT01030107
NCT01030107已完成不适用

Sleep Duration and Pediatric Overweight: the Role of Eating Behaviors

The Miriam Hospital1 个研究点 分布在 1 个国家目标入组 37 人开始时间: 2009年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
37
试验地点
1
主要终点
absolute reinforcing value of food as compared to sedentary activities

研究概览

简要总结

The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
8 Years 至 11 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age 8-11 years old
  • BMI for age and gender > 5th percentile (but no greater than 100% overweight)
  • Sleep approximately 9-10 hours nightly
  • Attend elementary school
  • Like at least 1 food and 1 activity used in the reinforcement paradigm
  • Able to understand and complete the reinforcement paradigm

排除标准

  • Existence of a diagnosable sleep disorder
  • Medical or psychiatric condition that could influence sleep or weight
  • Onset of menarche
  • Inability to complete study materials, including diagnosed disabilities
  • Dietary restrictions/allergies to foods used in the study that preclude them from study participation

结局指标

主要结局

absolute reinforcing value of food as compared to sedentary activities

时间窗: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration

次要结局

  • subjective ratings of hunger and appetite(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • caloric intake(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • plasma levels of leptin and ghrelin(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)
  • levels of physical activity(after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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