Effects of Sleep Duration on Eating and Activity Behaviors

Completed

• Conditions: Sleep; Obesity
• Interventions: Behavioral: Increase Sleep; Behavioral: Decrease Sleep

• Registration Number: NCT01030107
• Lead Sponsor: The Miriam Hospital

Brief Summary

The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-02
• Study First Submitted: 2009-12-09
• Study First Submitted QC: 2009-12-10
• Study First Posted: 2009-12-11
• Status Verified: 2011-04
• Primary Completion: 2012-01
• Study Completion: 2012-01
• Last Update Submitted: 2012-10-04
• Last Update Posted: 2012-10-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Age 8-11 years old
• BMI for age and gender > 5th percentile (but no greater than 100% overweight)
• Sleep approximately 9-10 hours nightly
• Attend elementary school
• Like at least 1 food and 1 activity used in the reinforcement paradigm
• Able to understand and complete the reinforcement paradigm

Exclusion Criteria

• Existence of a diagnosable sleep disorder
• Medical or psychiatric condition that could influence sleep or weight
• Onset of menarche
• Inability to complete study materials, including diagnosed disabilities
• Dietary restrictions/allergies to foods used in the study that preclude them from study participation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Children with Insufficient Sleep	Decrease Sleep	Children who sleep approximately 9-10 hours/night
Children with Insufficient Sleep	Increase Sleep	Children who sleep approximately 9-10 hours/night

Primary Outcome Measures

Name	Time	Method
absolute reinforcing value of food as compared to sedentary activities	after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration

Secondary Outcome Measures

Name	Time	Method
caloric intake	after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration
subjective ratings of hunger and appetite	after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration
plasma levels of leptin and ghrelin	after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration
levels of physical activity	after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration

Trial Locations

Locations (1)

Weight Control and Diabetes Research Center; 🇺🇸 Providence, Rhode Island, United States