Sleep, Biological Stress, and Health Among Toddlers Living in Socioeconomically Disadvantaged Homes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Caregiver report
研究概览
简要总结
A longitudinal study to examine the relationships among sleep characteristics, stress, and child behavior problems in a community sample of toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically disadvantaged homes
详细描述
The purpose of this study is to examine the relationships among sleep characteristics, stress (allostatic load), and health among toddlers living in economically stressed communities. Sleep difficulty, including short sleep duration and poor sleep efficiency, is closely related to measures of stress, including interleukin (IL-6), cortisol, c-reactive proteins (CRP), secretory immunoglobulin A (SIgA), and body mass index (BMI) and may therefore contribute to 'wear and tear' on the body (allostatic load), a problem that places children at high risk of physical and mental health problems. Young children who live with socioeconomic adversity are especially vulnerable to both sleep difficulty and higher levels of physiologic stress (allostatic load).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Months 至 15 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically disadvantaged homes.
排除标准
- •If the toddler has a diagnosis of sleep apnea or has another documented medical condition affecting sleep.
结局指标
主要结局
Caregiver report
时间窗: 12 to 36 months
Caregivers will complete the Brief Infant Sleep Questionnaire
Behavioral monitoring
时间窗: 12 to 36 months
Toddler behavior problems will be assessed using the Brief Infant Toddler Social and Emotional Assessment (BITSEA).
Sleep monitoring
时间窗: 9 days
Sleep characteristics will be measured by an accelerometer on the wrist or ankle to measure sleep efficiency.
Sleep diary
时间窗: 12 to 24 months
Caregivers will complete a sleep diary to record their toddler's sleep for time period when an accelerometer will be worn by the child.
次要结局
- Immune biomarkers(12 to 24 months)
- Anthropometric biomarkers(12 to 24 months)
- Cortisol biomarker(12 to 24 months)