Sleep, Biological Stress, and Health Among Toddlers Living in Socioeconomically Disadvantaged Homes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sleep Disorder
- Sponsor
- Yale University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Caregiver report
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
A longitudinal study to examine the relationships among sleep characteristics, stress, and child behavior problems in a community sample of toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically disadvantaged homes
Detailed Description
The purpose of this study is to examine the relationships among sleep characteristics, stress (allostatic load), and health among toddlers living in economically stressed communities. Sleep difficulty, including short sleep duration and poor sleep efficiency, is closely related to measures of stress, including interleukin (IL-6), cortisol, c-reactive proteins (CRP), secretory immunoglobulin A (SIgA), and body mass index (BMI) and may therefore contribute to 'wear and tear' on the body (allostatic load), a problem that places children at high risk of physical and mental health problems. Young children who live with socioeconomic adversity are especially vulnerable to both sleep difficulty and higher levels of physiologic stress (allostatic load).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Toddlers (12-24 months- ages 12-15 months at enrollment) living in socioeconomically disadvantaged homes.
Exclusion Criteria
- •If the toddler has a diagnosis of sleep apnea or has another documented medical condition affecting sleep.
Outcomes
Primary Outcomes
Caregiver report
Time Frame: 12 to 36 months
Caregivers will complete the Brief Infant Sleep Questionnaire
Behavioral monitoring
Time Frame: 12 to 36 months
Toddler behavior problems will be assessed using the Brief Infant Toddler Social and Emotional Assessment (BITSEA).
Sleep monitoring
Time Frame: 9 days
Sleep characteristics will be measured by an accelerometer on the wrist or ankle to measure sleep efficiency.
Sleep diary
Time Frame: 12 to 24 months
Caregivers will complete a sleep diary to record their toddler's sleep for time period when an accelerometer will be worn by the child.
Secondary Outcomes
- Immune biomarkers(12 to 24 months)
- Anthropometric biomarkers(12 to 24 months)
- Cortisol biomarker(12 to 24 months)