NCT02040701
Unknown
Not Applicable
Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sleep Disordered Breathing (SDB)
- Sponsor
- Tel-Aviv Sourasky Medical Center
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Plasma inflammatory-markers
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children.
In addition, to measure markers of local inflammation and to evaluate the response to treatment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •children ages 6 months-18 years
- •suspected sleep-disordered breathing or will attend the pre-operative ENT clinic for adenoidectomy or adenotonsillectomy
Exclusion Criteria
- •craniofacial abnormalities
- •neurological disorders
- •genetic disorders
- •infectious disease
- •chronic inflammatory disease
- •any underlying chronic medical condition
Outcomes
Primary Outcomes
Plasma inflammatory-markers
Time Frame: After the blood analyzed
Sleep disordered breathing (SDB) in children is associated with increased markers of inflammation, atherogenesis and oxidative stress.
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Identification of Sleep-Disordered Breathing in ChildrenSleepSleep Apnea SyndromesSleep Disordered BreathingNCT00233194University of Michigan160
Completed
Not Applicable
Hypertension and Sleep Disordered Breathing in PediatricsHypertensionObstructive Sleep ApneaNCT00990899NYU Langone Health24
Completed
Not Applicable
Prevalence of Sleep-Disordered Breathing in ChildrenLung DiseasesSleep Apnea SyndromesNCT00022789Milton S. Hershey Medical Center700
Active, not recruiting
Not Applicable
Idiopathic Scoliosis Progression and Sleep-disordered Breathing in ChildrenScoliosis IdiopathicSleep Disordered BreathingObstructive Sleep ApneaNCT03858244Second Affiliated Hospital of Wenzhou Medical University405
Unknown
Not Applicable
Screening for Sleep Disordered Breathing With Minimally Obtrusive SensorsSleep Apnea SyndromesSnoringNCT02470182Oregon Health and Science University52