NCT02040701UnknownNot Applicable
Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress
Tel-Aviv Sourasky Medical Center1 site in 1 country300 target enrollmentStarted: May 2006Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Plasma inflammatory-markers
Study Overview
Brief Summary
The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children.
In addition, to measure markers of local inflammation and to evaluate the response to treatment.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 6 Months to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •children ages 6 months-18 years
- •suspected sleep-disordered breathing or will attend the pre-operative ENT clinic for adenoidectomy or adenotonsillectomy
Exclusion Criteria
- •craniofacial abnormalities
- •neurological disorders
- •genetic disorders
- •infectious disease
- •chronic inflammatory disease
- •any underlying chronic medical condition
Outcomes
Primary Outcomes
Plasma inflammatory-markers
Time Frame: After the blood analyzed
Sleep disordered breathing (SDB) in children is associated with increased markers of inflammation, atherogenesis and oxidative stress.
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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