The Effect of Premedication With Intravenous Lornoxicam on Propofol Injection Pain At Induction of General Anaesthesia in Adults.

Not Applicable

• Conditions: Propofol Injection Pain; Anaesthesia

• Registration Number: PACTR201705002263637
• Lead Sponsor: Post Graduate Medical Education Programme

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 156

Inclusion Criteria

Adult patients aged 18 to 65 years
ASA physical status 1 and 2

Exclusion Criteria

Systemic Arterial Hypertension.
Pregnancy.
History of or active phlebitis/thrombophlebitis.
Allergy or hypersensitivity (asthma, rhinitis, angioedema or urticaria) to lornoxicam and any of its excipients.
Presence of any contraindication to NSAID use and particularly:
Renal disease/renal impairment
Hypersensitivity to any other NSAIDs
Documented thrombocytopenia
Gastro-intestinal bleeding, cerebrovascular bleeding or other bleeding disorders
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy
Active or history of recurrent peptic ulcer/haemorrhage
Severe hepatic impairment
Severe heart failure.
Patients already on other NSAID therapy.
Language barriers in eexplaining study plan and obtaining consent.
Difficult venous access (more than 2 attempts and/or Patients presenting for emergency surgery.
Patients in pain.
ASA physical status 3 and 4.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity of propofol injection pain.

Secondary Outcome Measures

Name	Time	Method
Incidence of propofol injection pain