To Compare the Crystallization Patterns in Blood Samples of Oral Submucous Fibrosis, Oral Cancer and Healthy Individuals
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynxHealth Condition 2: K135- Oral submucous fibrosis
- Registration Number
- CTRI/2024/02/062193
- Lead Sponsor
- MGM Dental college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Group I- Clinically diagnosed cases of Oral submucous fibrosis
Group II- Clinicopathologically diagnosed cases of Oral Squamous Cell Carcinoma
Group III- Healthy individuals advised for blood investigations for routine dental surgical procedures without any known medical history
Group I-
1.Patients undergoing treatment for OSMF
2.Patient with history of scleroderma, amyloidosis, generalized fibromatosis.
3. Patients with systemic conditions like heart diseases, diabetes mellitus, thyrotoxicosis, liver diseases, pregnancy, oestrogen therapy, etc.
4.Patients those who are not willing to participate.
Group II
1. Recurrent cases of oral squamous cell carcinoma
2. Patients undergoing /undergone treatment of OSCC.
3. Patients with systemic conditions like heart diseases, diabetes mellitus, thyrotoxicosis, liver diseases, pregnancy, oestrogen therapy, etc
4. Patients diagnosed other than OSCC after histopathological examination.
5. Patients those who are not willing to participate.
Group III
1. Patients those who are not willing to participate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Evaluate and Compare the Crystallization Patterns in Oral Submucous Fibrosis, Oral Squamous Cell Carcinoma and Healthy IndividualsTimepoint: Blood samples will be collected at the time of patient presentation from Oral Submucous Fibrosis Oral Squamous Cell Carcinoma patients and healthy individuals. The crystallization patterns will be observed 24 hours after the sample collection and crystallization patterns of oral submucous fibrosis and oral squamous cell carcinoma will be compared with the crystallization patterns of healthy individuals
- Secondary Outcome Measures
Name Time Method To compare the crystallization patterns in different clinical stages in Oral Submucous Fibrosis Cases.Timepoint: After taking a patients informed consent detailed case history will be taken for study group & blood samples will be collected