Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- the time to first gas passing after surgery
研究概览
简要总结
The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to compare the effect of epidural analgesia and intravenous analgesia on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient between 20 and 70 of age with ASA physical status Ⅰ-Ⅲ
- •gastric cancer patient undergoing laparoscopic gastrectomy
排除标准
- •ASA physical status Ⅳ
- •bradycardia (< 60 bpm), arrhythmia
- •uncompensated heart failure
- •hepatic failure (Child-Pugh score B)
- •renal failure (eGFR MDRD < 60 ml/min/1.73m2)
研究组 & 干预措施
continuous epidural analgesia group
干预措施: continuous epidural analgesia (Other)
continuous intravenous analgesia group
干预措施: continuous intravenous analgesia (Other)
结局指标
主要结局
the time to first gas passing after surgery
时间窗: within 5days after surgery
Outcome will be assessed by a investigator blinded to the study group.
the time to resume water intake after surgery
时间窗: within 5days after surgery
Outcome will be assessed by a investigator blinded to the study group.
soft diet intake after surgery
时间窗: within 5days after surgery
Outcome will be assessed by a investigator blinded to the study group.
次要结局
- postoperative pain(immediately after surgery to 48 hours)