A STUDY ON KIDNEY FUNCTION AND FACTORS POINTING AT ACUTE KIDNEY INJURY AFTER KIDNEY STONE REMOVAL SURGERY
- Conditions
- Calculus of kidney,
- Registration Number
- CTRI/2022/03/040840
- Lead Sponsor
- KMC MANIPAL
- Brief Summary
The present study will be conducted on diagnosed patients of renal calculus disease getting admitted to Kasturba Medical College, Manipal.
ï‚· Patients will be selected for study according to all inclusion and exclusion criteria.
ï‚· Each patients renal status on admission will be recorded whether Normal,AKI,CKD,AKI ON CKD, and 3 moths prior status of renal functions.
 The purpose of the study will be explained to the patient and informed consent will be obtained for collection of data in patient’s own vernacular language.
ï‚· PNL protocols will be followed for evaluation, treatment and follow-up.
 Demographic data like age, gender, body mass index (BMI), comorbidities including hypertension, diabetes mellitus, drug history of angiotensin converting enzyme inhibitors (ACE inhibitor), angiotensin II receptor blockers and beta blockers,NSAID’s.
ï‚· Laboratory data include serial serum creatinine pre- and postoperation (12, 24, 48 h), hemoglobin (Hb), total leucocyte count (TLC),neutrophil lymphocyte ratio (NL ratio ),platelet lymphocyte ratio (PL ratio) Prothrombin time (PT), serum uric acid and urine culture.
ï‚· Stone factors assessed by noncontrast computerized tomography of kidneys, ureter and bladder (NCCT KUB) and includes stone burden in cubic millimeters (volume = LxWxD), location and Hounsfield values and laterality.
ï‚· The intraoperative factors includes puncture site, tract size, tract number, operative time, the need for blood transfusion, stone clearance, usage of ureteral stent or nephrostomy tube and intra op hypotension any ancillary procedures.
 Postoperative complications were documented using the modified Clavien–Dindo grading system.
Patients will be followed up after one month with USG KUB/ X-ray KUB.
ï‚· Patients with postoperative AKI were followed up with serial creatinine values up to 3 months.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 385
All patients undergoing PCNL procedure >18years.
Pregnant women Bleeding diathesis Ureteral calculi.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To analyse the incidence of post-PNL AKI The Incidence And The Risk Factors Can Only Be Analysed At The End Of The Study 2. To analyse potential risk factors and outcomes The Incidence And The Risk Factors Can Only Be Analysed At The End Of The Study
- Secondary Outcome Measures
Name Time Method 1. To analyse renal function in patients with nephrolithiasis This Is Done At The Begning Of The Study On The 1 st Day Of Admission
Trial Locations
- Locations (1)
Kasturba hospital
🇮🇳Udupi, KARNATAKA, India
Kasturba hospital🇮🇳Udupi, KARNATAKA, IndiaGoli Venkata Sai AbhishekPrincipal investigator7674965678abhishekgoli897@gmail.com