Effect of High-intensity Interval Training on Cardiometabolic Health and Physical Fitness in Young Adults With Obesity
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Body fat percentage
研究概览
简要总结
The objective of the present project is to compare the effects of two types of training on cardiovascular health components and physical fitness in young adults with obesity.
详细描述
Obesity represents a serious public health problem, and its prevalence continues to rise worldwide. Numerous studies have documented the positive effects of moderate-intensity continuous training (MICT) on cardiovascular and metabolic health in individuals living with obesity; however, the effects of high-intensity interval training (HIIT) are still being explored.
Therefore, the objective of the present research protocol is to analyze and compare the effects of an MICT program and an HIIT program on cardiometabolic biomarkers and physical fitness in young adults with obesity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Young adults
- •BMI ≥ 30 kg/m^2" and < 40 kg/m^2
- •Signed informed consent form
排除标准
- •Participants who smoke
- •Clinical diagnosis of hypothyroidism
- •Clinical diagnosis of type 1 diabetes mellitus
- •Clinical diagnosis of type 2 diabetes mellitus
- •Clinical diagnosis of grade 3 obesity
- •Clinical diagnosis of hypertension
- •Clinical diagnosis of acute myocardial infarction or angina pectoris
- •Use of nitrates and calcium channel blockers within 4 days prior to the start of the study
- •Use of beta-blockers or hypoglycemic agents within 7 days prior to the intervention
- •Pregnant women
- •Breastfeeding women
- •Men consuming more than 40 g of alcohol per day or women consuming more than 20 g per day
- •Postural and biomechanical disorders (knee, foot, and spine)
结局指标
主要结局
Body fat percentage
时间窗: Baseline and after 12 weeks
Body fat percentage (%): Changes in body fat assessed by bioelectrical impedance analysis (BIA)
Maximum oxygen uptake (VO₂max)
时间窗: Baseline and after 12 weeks
VO₂max (ml/min/kg): Change from Baseline at 12 weeks, measured using a submaximal exercise test based on the Åstrand-Ryhming protocol
Muscle mass percentage
时间窗: Baseline and after 12 weeks
Muscle mass percentage (%): Changes in muscle mass measured using bioelectrical impedance analysis (BIA)
Weight
时间窗: Baseline and after 12 weeks
Weight (kg): Changes in weight from baseline to 12 weeks of intervention.
Height
时间窗: Baseline and after 12 weeks
Height (cm): Changes in height from baseline to 12 weeks of intervention.
Body mass index (BMI)
时间窗: Baseline and after 12 weeks
BMI (kg/m2): Change from Baseline at 12 weeks, calculated by: weight (kg)/ height (m\^2)
Waist circumference
时间窗: Baseline and after 12 weeks
Waist circumference (cm): Changes in waist circumference will be measured using a Lufkin measuring tape (USA) following the guidelines of the International Society for the Advancement of Kinanthropometry (ISAK)
Waist-to-hip ratio
时间窗: Baseline and after 12 weeks
Waist-to-hip ratio: Changes in waist-to-hip ratio will be calculated by dividing the waist measurement by the hip measurement
Glucose
时间窗: Baseline and after 12 weeks
Glucose (mg/dl): Changes from baseline to 12 weeks of intervention
Triglycerides
时间窗: Baseline and after 12 weeks
Triglycerides (mg/dl): Changes from baseline to 12 weeks of intervention
Total cholesterol
时间窗: Baseline and after 12 weeks
Total cholesterol (mg/dl): Changes from baseline to 12 weeks of intervention
HDL cholesterol
时间窗: Baseline and after 12 weeks
HDL cholesterol (mg/dl): Changes from baseline to 12 weeks of intervention
LDL cholesterol
时间窗: Baseline and after 12 weeks
LDL cholesterol (mg/dl): Changes from baseline to 12 weeks of intervention
C-reactive protein (CRP)
时间窗: Baseline and after 12 weeks
CRP (mg/dl): Changes from baseline to 12 weeks of intervention
Systolic blood pressure (SBP)
时间窗: Baseline and after 12 weeks
SBP (mmHg): Changes from baseline to 12 weeks of intervention
Diastolic blood pressure (DBP)
时间窗: Baseline and after 12 weeks
DBP (mmHg): Changes from baseline to 12 weeks of intervention
次要结局
未报告次要终点
研究者
José Manuel Pérez Casillas
Principal Investigator
Centro Universitario de Tlajomulco, Universidad de Guadalajara