Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Completed

• Conditions: Drug Interaction

• Registration Number: NCT04078620
• Lead Sponsor: Zagazig University

Brief Summary

Drug drug interactions is frequent in critically ill patients due to polypharmacy, different drug groups and prolonged ICU or hospital stay

Detailed Description

This cross sectional study was conducted in Surgical ICU, zagazig University Hospital for 6months period.

Demographic data (age, gender),clinical history data (main diagnosis, ICU stay in days, transfer from emergency room or other departments, on mechanical ventilation or not, state of consciousness

Study Timeline

• Study Start: 2018-06-15
• Primary Completion: 2019-01-15
• Study Completion: 2019-04-20
• Status Verified: 2019-08
• Study First Submitted: 2019-08-25
• Study First Submitted QC: 2019-09-01
• Last Update Submitted: 2019-09-01
• Study First Posted: 2019-09-06
• Last Update Posted: 2019-09-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• all patients admitted to Surgical ICUs for six months period

Exclusion Criteria

• less than one day admission to ICU,not completed data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of Drug interactions by Lexicomp interactions application	6months period	Lexicomp interactions classified As: A(no known interactions) B(no action needed) C(monitor therapy) D(consider therapy modification) X (avoid combination)
Severity of Drug interactions by Medescape interactions checker:	6months period	Interactions classified with Medescape interactions checker as :(contraindicated, serious use alternative, monitor closely,minor)

Trial Locations

Locations (1)

Liza Elsayed Ali; 🇪🇬 Zagazig, Sharquia, Egypt