The effect of ICU-tailored drug-drug interaction (DDI) alerts on medication prescribing and monitoring
Recruiting
- Conditions
- drug-drug interactions, clinical decision support systems, intensive care, medication safety
- Registration Number
- NL-OMON28748
- Lead Sponsor
- Amsterdam UMC locatie AMC (AMC-UvA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 9000
Inclusion Criteria
partcipating ICUs: Dutch Intensive Care Units using Metavision as a patient data management system.
Exclusion Criteria
Patients: patients admitted to one of the participating ICUs under the age of 18 will be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in the incidence of clinically relevant potential drug-drug interactions per 1000 medication administrations
- Secondary Outcome Measures
Name Time Method - The number of (clinically relevant) potential drug-drug <br> interactions per patient<br /><br /><br><br>- The proportion of patients admitted to the ICU with at <br> least one (clinically relevant) potential drug-drug <br> interactions<br /><br /><br><br>- ICU length of stay <br /><br /><br><br>- The override rate of (clinically relevant) potential drug- <br> drug interaction alerts <br /><br /><br><br>- The number of ADEs related to drug-drug interactions <br> per 1000 medication administrations<br /><br /><br><br>-The proportion of appropriately handled clinically relevant potential drug-drug interactions<br>