NCT00024076已完成2 期
Radiofrequency Ablation of Pulmonary Malignancy
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
研究概览
简要总结
RATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. CT-guided radiofrequency ablation may be effective treatment for lung cancer.
PURPOSE: Phase II trial to study the effectiveness of radiofrequency ablation in treating patients who have refractory or advanced lung cancer.
详细描述
OBJECTIVES:
- Determine the safety and toxicity of radiofrequency ablation in patients with refractory or advanced pulmonary malignancies.
- Determine the efficacy of this treatment, in terms of local control, in these patients.
- Determine whether CT scan is a reasonable imaging assessment tool for treatment delivery and follow-up in these patients.
OUTLINE: Patients undergo percutaneous CT-guided radiofrequency ablation directly to the tumor over 2 hours.
Patients are followed at 1, 3, 6, and 12 months.
PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of a primary or secondary intrathoracic malignancy
- •Any cell type or origin
- •Involving the intrapulmonary, mediastinal, or pleural/chest wall
- •Inoperable primary or metastatic cancer to the lung
- •Refractory to or not amenable to conventional therapy (e.g., surgery, chemotherapy, or radiotherapy)
- •Single or multiple lesions that are non-contiguous with vital structures or organs such as:
- •Great vessels
- •Esophagus
- •Less than 5 cm in largest dimension
- •Accessible via percutaneous transthoracic route
- •Coagulation profile normal
排除标准
- 未提供
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
Radiofrequency Ablation in Treating Patients Who Are Undergoing Surgery for Thyroid CancerHead and Neck CancerNCT00103155University of California, San Francisco
已完成
不适用
PET Scan and CT Scan in Evaluating Response in Patients Undergoing Radiofrequency Ablation for Lung MetastasesMetastatic CancerUnspecified Adult Solid Tumor, Protocol SpecificNCT00382252Institut Bergonié89
已完成
2 期
Radiofrequency Ablation During Surgery in Treating Patients With Non-Small Cell Lung CancerLung CancerNCT00039507Fox Chase Cancer Center
已完成
不适用
Radiofrequency Ablation in Treating Patients With Liver Cancer and CirrhosisLiver CancerNCT00132041American College of Radiology Imaging Network51
终止
2 期
Radiofrequency Ablation in Treating Patients With Unresectable Primary or Metastatic Liver CancerMetastatic CancerUnspecified Adult Solid Tumor, Protocol SpecificLiver CancerNCT00019604National Institutes of Health Clinical Center (CC)44