MedPath

The Effect of Topical Application of 5-fluorouracil during Functional Endoscopic Sinus Surgery(FESS) in the prevention of nasal adhesions post-surgery.

Not Applicable
Not yet recruiting
Conditions
Health Condition 1: A488- Other specified bacterial diseases
Registration Number
CTRI/2021/03/032286
Lead Sponsor
Dr Lekhaa M
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1 Patients of either age between 18 to 60 years

2 Diagnosis of bilateral chronic sinusitis who have had no relief with maximum medical therapy

3 Similar Lund Makay Scoring on both sides

Exclusion Criteria

Revision Endoscopic Sinus surgery

Uncontrolled systemic illness

Known allergy to 5 FU

Pregnancy and lactation

Pre-existing septal perforation or adhesion

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Formation of adhesions post-operativelyTimepoint: At 2nd 4th and 12th week postoperatively
Secondary Outcome Measures
NameTimeMethod
Reduction in formation of nasal crusting postoperativelyTimepoint: At 2nd 4th and 12th week postoperatively
© Copyright 2025. All Rights Reserved by MedPath