Phenylephrine to prevent pressure drop in obese pregnant women who underwent cesarean sectio

Phase 4

Recruiting

• Conditions: Pregnancy; Maternal Obesity; Hypotension; Cesarean; G08.686.784.769; C13.703.417; C14.907.514; E04.520.252.500

• Registration Number: RBR-42dch5
• Lead Sponsor: Hospital Universitário Júlio Muller

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Obese pregnant women with a body mass index greater than or equal to 30 Kg / m2 candidates for elective cesarean section under spinal anesthesia, classified in Physical State II to III of the American Society of Anesthesiologists (ASA) who sign the written, free and informed consent.

Exclusion Criteria

Age less than 18 years; gestational age less than 37 weeks; hypertensive pregnancy disease, defined as systolic blood pressure (SBP) greater than 140 mmHg or diastolic blood pressure (DBP) greater than 90 mmHg; twinning; intrauterine growth retardation; cardiovascular disease class II above the New York Heart Association; cerebrovascular disease, fetal abnormality and contraindications to spinal anesthesia (e.g., hemodynamic instability, infection at the lumbar puncture site, coagulopathy and spinal neurological disease).

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find a 50% reduction in hypotension episodes in patients who receive intravenous phenylephrine infusion.

Secondary Outcome Measures

Name	Time	Method
40% reduction in nausea and vomiting episodes in patients with phenylephrine infusion.