A clinical trial to study the effect of phenylephrine, a drug that increases blood pressure, to prevent decrease in blood pressure following oxytocin injection during planned caesarean sectio
- Conditions
- Health Condition 1: null- Oxytocin induced hypotension and tachycardia
- Registration Number
- CTRI/2016/01/006548
- Lead Sponsor
- niversity College of Medical Sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 66
• Healthy term pregnant patients undergoing elective caesarean section under spinal anaesthesia
• Uncomplicated, singleton pregnancy
• Patients in active labour
• Ruptured membranes
• Known drug allergy to oxytocin
• Maternal complications e.g. pre-eclampsia, diabetes mellitus, cardiovascular disease, cerebrovascular disease
• Known risk factors for postpartum haemorrhage e.g. Multiple gestation, abnormal placentation, uterine fibroid, macrosomia, hydramnios, history of postpartum haemorrhage or uterine atony
• Patients with absolute or relative contra-indications for spinal anaesthesia e.g. infection in lumbar area, coagulation abnormalities, autonomic neuropathy, spinal deformities, other neurological diseases or hypovolemia due to any cause
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Peak changes in mean arterial pressure and heart rateTimepoint: Peak changes in mean arterial pressure and heart rate
- Secondary Outcome Measures
Name Time Method a)Changes in systolic blood pressure and diastolic blood pressure <br/ ><br>b)Any complications observed <br/ ><br>Timepoint: a)Initial 3 minutes following oxytocin administration <br/ ><br>b)After delivery