Effects of a Nordic breakfast on cardiovascular risk factors.

Completed

Conditions: Cardiovascular risk factors
Nutritional, Metabolic, Endocrine
Disorders of lipoprotein metabolism and other lipidaemias

Registration Number: ISRCTN84550872

Lead Sponsor: niversity of Uppsala (Sweden)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 88

Inclusion Criteria

1. Slightly overweight and hyperlipidemic but otherwise healthy as assessed by the results of the screening laboratory tests and judged by medical staff
2. Age = 25 and = 67 years at visit 1
3. Body Mass Index (BMI) = 25 and = 35 kg/m2
4. LDL cholesterol = 3.0 mmol/l
5. Haemoglobin (Hb) = 120 g/l for women and = 130 g/l for men
6. Signed written informed and biobank consents

Exclusion Criteria

1. Participation in a clinical study with blood sampling within 90 days prior to screening visit and throughout the study.
2. Use of cholesterol lowering medication <3 months prior screening visit.
3. Blood pressure >155/95 (will be measured at visit 1 for inclusion).
4. Consumption of products or supplements fortified with plant sterols or omega-3 or omega-6 or omega 9- fatty acids within 3 weeks prior to the visit 1 and no consumption at all throughout the study.
5. Allergic to certain foods
6. Slimming or medically prescribed diet/medication or a special diet (vegan and gluten-free).
7. Not able to eat porridge for breakfast every day during 12 weeks
8. Not able to eat herring or mackerel for breakfast 3 days/week during 12 weeks
9. Pregnant or lactating or wish to become pregnant during the period of the study.
10. Lack of suitability for participation in the study for any reason as judged by the personnel at Good Food Practice (GFP) research clinic.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect on LDL-cholesterol will be measured at baseline, 6 and 12 weeks.

Secondary Outcome Measures

Name	Time	Method
The following will be measured at baseline, 6 and 12 weeks<br>1. HDL cholesterol<br>2. Total cholesterol<br>3. Triglycerides<br>4. High-Sensitivity C-Reactive Protein (HS-CRP)<br>5. Apolipoprotein A1 and B<br>6. Blood pressure<br>7. Sagittal abdominal diameter (SAG) <br>8. Hip<br>9. Waist <br>10. Glycated Haemoglobin (HbA1c) <br>The following will be measured at baseline and 12 weeks<br>11. Glucose response <br>12. Insulin sensitivity