Effects of a Nordic Diet on cardiovascular risk factors

Completed

• Conditions: Cardiovascular risk factors; Circulatory System

• Registration Number: ISRCTN77759305
• Lead Sponsor: niversity of Uppsala (Sweden)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-12-15
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

1. Men and women between 25 and 65 years of age
2. Healthy as assessed by a physician
3. Body mass index (BMI) greater than or equal to 20 and less than or equal to 31 kg/m^2
4. Plasma low density lipoprotein cholesterol (LDL-C) greater than or equal to 3.5 mmol/l
5. Haemoglobin (Hb) greater than or equal to 120 g/l for women and greater than or equal to 130 g/l for men

Exclusion Criteria

1. Participation in a clinical study within 90 days prior to screening visit and throughout the study
2. Use of lipid lowering drugs two months prior screening and throughout the study
3. Blood pressure greater than 145/85 mmHg
4. Use of products or supplements fortified with plant sterols, omega-3, omega-6 or omega-9 fatty acids within 3 weeks prior to baseline visit
5. Allergy to certain foods
6. Weight-loss diets or drugs
7. Special diets (e.g. vegan and gluten free)
8. Pregnant or lactating

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in plasma LDL-C after 6 weeks

Secondary Outcome Measures

Name	Time	Method
Change in:<br>1. Other blood lipids and apolipoproteins<br>2. Blood pressure<br>3. Insulin sensitivity (fasting insulin and homeostatic model assessment insulin resistance [HOMA-IR])