KCT0000353
Not yet recruiting
未知
A Multicenter Clinical Study of Dementia, Mild Cognitive Impairment, and Subjective Memory Impairment: A CREDOS (Clinical Research Center for Dementia of South Korea) Study
ConditionsDiseases of the nervous system
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the nervous system
- Sponsor
- Inha University Hospital
- Enrollment
- 3000
- Status
- Not yet recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Alzheimer's disease
- •1\) Dementia by DSM\-IV
- •2\) Probable AD by NINCDS\-ADRDA
- •3\) Slowly progressive cognitive decline, at least for 6 months
- •2\. Subcortical Vascular Dementia (SVD)
- •1\) vascular dementia as described by the DSM\-IV
- •2\) has at least one focal neurologic sign
- •3\) severe ischemic changes on brain MRI
- •1\) No dementia or normal
- •2\) Memory complaint by subject or study partner
Exclusion Criteria
- •1\) Blindness or hearing loss to be unable to be tested
- •2\)sick\-sinus syndrome, a second or third degree atrioventricular block
- •3\)severe pulmonary disease (acute, severe, or unstable asthma, severe COPD)
- •4\)an active gastric ulcer
- •5\)uncontrolled diabetes mellitus
- •6\)severe hepatic, or renal disease
- •7\)uncured malignancy
- •8\)major depressive disorder, psychosis
- •9\)mental retardation
- •10\)a history of encephalitis
Outcomes
Primary Outcomes
Not specified
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