A longitudinal cohort study of dementia with Lewy bodies - Unravelling the confounding influences of Alzheimer’s disease and cerebrovascular disease in dementia with Lewy bodies.

Walter and Eliza Hall Institute of Medical Research0 sites160 target enrollmentFebruary 9, 2018

Overview

No summary available.

Registry

who.int

Start Date

February 9, 2018

End Date

TBD

Last Updated

4 years ago

Study Type

Observational

Sex

All

Sponsor

Walter and Eliza Hall Institute of Medical Research

•DLB/PDD/AD participants:
•Fulfills clinical diagnostic criteria for probable dementia with Lewy bodies (DLB)
•Fulfills clinical diagnostic criteria for probable Parkinson's disease dementia (PDD)
•Fulfills clinical diagnostic criteria for probable Alzheimer's disease (AD)
•Male or female aged 50\+
•MMSE greater than or equal to 14
•no past history of alcohol or drug dependence
•english as first language or adequate understanding for cognitive testing
•adequate visual and auditory acuity to perform neuropsychological testing
•Healthy Volunteers:

•DLB/PDD/AD participants:
•alcohol intake greater than 4 standard alcoholic drinks per day
•no identifiable family carer or other informant
•Healthy controls:
•No active, clinically significant psychiatric illness \- this can impact on cognition and would not be suitable as a healthy control comparison
•No severe medical illness that may impede study participation
•contraindications to MRI (e.g. pacemaker, stents, metal implants)