Immunologic response to Hepatitis B virus vaccination among Thai adult Human Immunodeficiency Virus infected patients without Hepatitis B virus infectio
Completed
- Conditions
- One dose of HBV vaccination might complete protective immunity in some of the HIV infected patients.Vaccine, Hepatitis B, HIV, vaccination, immunity
- Registration Number
- TCTR20210616005
- Lead Sponsor
- /A
- Brief Summary
Among the patients with HIV who take ART regularly, CD4 more than 200 cells/mm3, 21.6 percent of them have protective immunity to HBV after one dose of vaccination. The associated factors are age group (under 29 years old) and antiHBs titer 2- 10 mlU/mL prior to their vaccination.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 88
Inclusion Criteria
1.Patients older than 18 years
1.Eligible to receive vaccination blood test collection
2.HIV-infected and CD4 > 200 cell/mm3 for at least 6 months
3.All negative results in serology test for HBsAg, antiHBs and antiHBc
Exclusion Criteria
1.Failure to have their blood test collection for more than 1 appointment
2.Skin infection at the site of vaccination
3.Impossible vaccination due to personal problems
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of antiHBs 1 month after vaccination antiHBs titer
- Secondary Outcome Measures
Name Time Method Factors associated with the presence of protective antiHBs 1 month after vaccination antiHBs titer