Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Not Applicable

Completed

• Conditions: Vesicular Palmoplantar Eczema; Pompholyx
• Interventions: Drug: dandelion juice

• Registration Number: NCT00442091
• Lead Sponsor: Odense University Hospital

Brief Summary

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

Detailed Description

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.

The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Study Timeline

• Study First Submitted: 2007-02-28
• Study First Submitted QC: 2007-02-28
• Study First Posted: 2007-03-01
• Study Start: 2010-12
• Primary Completion: 2019-12
• Study Completion: 2019-12
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-02
• Last Update Posted: 2020-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

• Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

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Exclusion Criteria

• Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
• Pregnancy, lactation.
• Compositae contact allergy.
• Liver or gall bladder disease.
• Abnormal renal or hepatic blood tests.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
10 ml of dandelion juice twice daily	dandelion juice	-

Primary Outcome Measures

Name	Time	Method
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.	3-4 weeks

Secondary Outcome Measures

Name	Time	Method
Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).	3-4 weeks

Trial Locations

Locations (1)

Department of Dermatology, Odense University Hospital; 🇩🇰 Odense, Denmark