The Effect of Smoking on Dimensional Changes of Free Gingival Graft Around Dental Implants

Not Applicable

Completed

• Conditions: Free Gingival Graft; Smoking; Dental Implant
• Interventions: Procedure: Free gingival graft

• Registration Number: NCT04340830
• Lead Sponsor: Ege University

Brief Summary

There are studies investigating the dimensional changes following free gingival graft (FGG) around teeth with inadequate attached gingiva, however no study investigating the effect of smoking on dimensional changes following FGG around dental implants exists. In the present study, we hypothesized that smoking might increase the dimensional change of FGG around dental implants and affect the healing of donor site.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-09
• Primary Completion: 2017-08
• Study Completion: 2017-08
• Status Verified: 2020-04
• Study First Submitted: 2020-04-07
• Study First Submitted QC: 2020-04-07
• Last Update Submitted: 2020-04-07
• Study First Posted: 2020-04-10
• Last Update Posted: 2020-04-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Implants with inadequate attached gingiva on the buccal site, which placed in posterior region at least 1 year ago, and loaded with a fixed prosthetic restoration at least 6 months ago.

Exclusion Criteria

Implants with peri-implantitis, patients who had previously the soft or hard tissue graft surgery at the site in question, patients who had previously operated from the donor site, patients with systemic disease that may interfere with periodontal surgery, patients taking any medication that can prolong bleeding, patients with immune system disease, infectious diseases such as hepatitis or HIV, individuals under the age of 18, and women with pregnant or breastfeeding.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
smoker	Free gingival graft	Those consuming at least 10 cigarette a day for ten years were included in smoker group.
non-smoker	Free gingival graft	Patients who never smoke were included in non-smoker group. Patients who quit smoking were not included in this group.

Primary Outcome Measures

Name	Time	Method
dimensional change of free gingival graft	0,1, 3, 6 months	the changes in vertical dimension of free gingival graft was measured by functional and visual methods intra-orally by individual stents, and horizontal dimension of free gingival graft was measured on digital photographs using specific software.
change in total free gingival graft area	0, 7th day, 1,3, 6 months	total free gingival graft area was calculated on digital photographs using specific software.

Secondary Outcome Measures

Name	Time	Method
Depth of vestibule sulcus	0, 7th day, 1,3, 6 months
tissue thickness of recipient and donor sites	0, 7th day, 1,3, 6 months
VAS	0,1,2,3,4,5,6,7. days