The effects of cinnamon on lipid profile, liver enzymes,insulin resistance and hs-CRP inflammatory factor, in patients with Nonalcoholic Steatohepatitis
Phase 2
- Conditions
- onalcoholic steatohepatitis (NASH).Nonalcoholic steatohepatitis (NASH)
- Registration Number
- IRCT201207114010N9
- Lead Sponsor
- ational Nutrition and Food Technology Research Institute (NNFTRI)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Age, 18 - 65 years old; Abnormal serum transferase (ALT & AST more than 1/5 fold of normal range); Sonographic findings compatible with hepatic steatosis (degree 1 or more); NASH was diagnosed during previous 6 months; no history of alcohol consumption; absence of Pregnancy, lactation, and Professional athletic; absence of other hepatobiliary disorders, autoimmune disease, malignancies, and endocrine disorders; absence of taking any medications in last 3 months. Exclusion criteria: Evidence of any allergic reaction to cinnamon; pregnancy; disliking to continue study with any reason.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hs-CRP. Timepoint: at the beginning and at the last. Method of measurement: ELISA.;Cholestrol, TG, LDL-c, HDL-c. Timepoint: at the beginning and at the last. Method of measurement: Biochemistry.;ALT, AST, GGT. Timepoint: at the beginning and at the last. Method of measurement: Biochemistry.;FBS. Timepoint: at the beginning and at the last. Method of measurement: Biochemistry.;Insulin. Timepoint: at the beginning and at the last. Method of measurement: elaisa.;Insulin resistance. Timepoint: at the beginning and at the last. Method of measurement: formula.
- Secondary Outcome Measures
Name Time Method Waist circumference. Timepoint: at the beginning and at the last. Method of measurement: non stretch meter.;Weight and BMI. Timepoint: at the beginning and at the last. Method of measurement: Weight will be measured by Secca scale , BMI by formula.