Effect of cinnamon supplementation on body weight, body composition, lipid profile, blood glucose, inflammatory markers and thyroid hormones in postmenopausal women.

Not Applicable

• Conditions: Study conducted with postmenopausal women with overweight or obesity.Keywords: women, menopause, obesity, cinnamon.; M01.975; C18.654.726.500; B01.650.940.800.575.100.590.149.500; G08.686.157.500

• Registration Number: RBR-3cr9jh
• Lead Sponsor: niversidade Federal Fluminense

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-25
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women with 12 months of amenorrhea; overweight or obese; age between 45 and 59 years.

Exclusion Criteria

use of anticoagulants, anti-lipidemic, antihypertensive and oral hypoglycemic agents and insulin; patients with hepatic dysfunction; hormone replacement; who has had chemotherapy; who has allergy or hypersensitivity to cinnamon.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Supplementation with 2g of cinnamon (Cinnamomum zeilannicum) for 8 weeks will reduce body weight, increase lean body mass and reduce adipose tissue; will reduce total cholesterol, LDL-C, triglyceride and glycemia in postmenopausal women. Assessment of anthropometric nutritional status will be performed before and after supplementation, by measuring body weight, height and Body Mass Index (BMI); the body composition will be determined by dual beam x-ray absorptiometry (DEXA). Bioclin brand kits will be used to evaluate total cholesterol, LDL-c, and triglycerides. To evaluate glycemia the microplates will be read, using the equipment of the brand Biotek and model Synergy H1 Hybrid Reader. Student's t-test and Variance (ANOVA) analysis will be used to compare the mean within and between groups, respectively. Statistical significance will be considered p <0.05.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not expected.