Long-term Physical Training in Chronic Obstructive Pulmonary Disease
- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- Other: Physical training
- Registration Number
- NCT01537627
- Lead Sponsor
- Universidade Estadual de Londrina
- Brief Summary
Several impairing factors contribute to physical limitation in chronic obstructive pulmonary disease (COPD) as deconditioning, muscle dysfunction and physical inactivity. The available literature clearly indicates that these therapeutic targets benefit from exercise training in patients with COPD and, currently, the key point is not whether patients should or not exercise, but which is the specific contribution of each exercise modality to this population. About this topic, the characteristics of a physical training program to be offered to patients have been a point discussed among researchers in this field, although recently the high-intensity training has been recognized as superior in comparison to the low-intensity training. Literature also indicates that, in order to change the sedentary lifestyle of patients with COPD, long-term training programs are indicated. However, a doubt still remains: if long-term programs are one of the key points to reduce physical inactivity, it is not yet clear whether it is necessary to include high-intensity exercises in that long-term program. If the duration is the only factor influencing the outcomes of the program, thus the intensity of training could be reduced, increasing the adherence of patients to the protocol. Based on this hypothesis, the aim of this study is to compare the effects of two physical training protocols in a long-term rehabilitation program (6 months) in patients with COPD: a high-intensity protocol (based on endurance and resistive training) and a low-intensity protocol (based on callisthenic and breathing exercises training). It is expected that the results of this study contribute to the scientific literature by demonstrating whether low- and high-intensity training contribute equally to change the sedentary lifestyle of patients after a long-term exercise program.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 82
- Chronic obstructive pulmonary disease (COPD) diagnosis according to Global Initiative for Chronic Obstructive Lung Disease(GOLD)criteria
- Clinical stability (i.e. absence of acute exacerbation in the last 3 months)
- Absence of any unstable/severe cardiac,osteoarticular or neuromuscular disorders which could limit physical activities in daily life
- Non participation in pulmonary rehabilitation in the last year
- Being unable to attend the outpatient clinic three times per week
- Inability to understand or cooperate with the assessment methods
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Low-intensity training (LT) Physical training - High-intensity training (HT) Physical training -
- Primary Outcome Measures
Name Time Method Physical activity in daily life Up to 4 years Main variable: time spent in physical activities of at least moderate intensity (min/day)
- Secondary Outcome Measures
Name Time Method Dyspnea sensation Up to 4 years Borg scale
Functional exercise capacity Up to 4 years 6-minute walking test
Maximal exercise capacity Up to 4 years Incremental Shuttle Walking Test
Peripheral muscle force Up to 4 years 1-repetitium maximum and peak quadriceps torque
Respiratory muscle force Up to 4 years Maximal inspiratory and expiratory pressures
Body composition Up to 4 years Electrical Bioimpedance
Health-related quality of life Up to 4 years Chronic Respiratory Disease Questionnaire (CRDQ)
Functional status Up to 4 years London Chest Activity of Daily Living scale (LCADL)
Lung function Up to 4 years Post-bronchodilator simple spirometry
Trial Locations
- Locations (1)
Hospital Universitário Norte do Paraná (University Hospital Regional North of Parana)
🇧🇷Londrina, Parana, Brazil