The Effect of Sildenafil on Intrauterine Growth Restriction (IUGR) of Fetus with Gestational Age above 28 Weeks and Neonatal Outcomes

Phase 3

Completed

• Conditions: Intrauterine growth restriction (IUGR); Sildenafil Citrate; Fetus; Gestational age; Infant, Newborn

• Registration Number: TCTR20200526006
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-10-25
• Study Start: 2020-05-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Inclusion criteria were 1) pregnancy with gestational age above 28 weeks. 2) Occurrence of IUGR in fetal weight below 10% percentiles and AC less than 3%, and 3) Ultrasound indicating fetal vascular Doppler disorder.

Exclusion Criteria

Exclusion criteria were 1) Patients with unknown gestational age, 2) Having specific fetal anomalies, 3) Taking vasodilator drugs, 4) Multiple pregnancy, and 5) Smoking or alcohol use drugs pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Placental function 2 (Before and after intervention) Doppler ultrasound

Secondary Outcome Measures

Name	Time	Method
Intrauterine Growth Restriction (IUGR) 2 (Before and after intervention) Doppler Ultrasound