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The Epidemiology of Recurrent Spontaneous Abortion Associated With Thrombophilla

Conditions
Recurrent Pregnancy Loss
Registration Number
NCT02990390
Lead Sponsor
Shanghai First Maternity and Infant Hospital
Brief Summary

RSA is a multifactorial disorder resulting from genetic factors, anatomic factors, autoimmune disorders, endocrine dysfunction, thrombophilia, life style factors, and maternal infections. However, the underlying causes remain undetermined in up to 50% of cases. In this clinical cohort study, we intended to get an epidemiological evidence for patients with recurrent spontaneous abortion associated with thrombophilla.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
45000
Inclusion Criteria
  • Woman who had 2 miscarriages before 12(th) week of gestation.Signed consent form.
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Exclusion Criteria
  1. having experienced severe allergies, trauma history and/or operation history within 3 months;
  2. with a history of mental illness and/or family history of mental illness
  3. limb disabled
  4. taking medicine within one month
  5. suffering major events or having mood swings
  6. with a history of recurrent pregnancy loss
  7. having internal and surgical disease(after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine routine)
  8. chromosome aberrations in anyone of the couple.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
D-Dimerthrough study completion, an average of 3 year
Secondary Outcome Measures
NameTimeMethod
BMI in kg/m^2through study completion, an average of 3 year
platelet aggregation timethrough study completion, an average of 3 year
anticardiolipin antibodythrough study completion, an average of 3 year

Trial Locations

Locations (1)

Shanghai first Maternity and Infant health hospital, Tong Ji University

🇨🇳

Shanghai, China

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