NCT02990390Unknown不适用
Shanghai First Maternity and Infant Hospital
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 45,000
- 试验地点
- 1
- 主要终点
- D-Dimer
研究概览
简要总结
RSA is a multifactorial disorder resulting from genetic factors, anatomic factors, autoimmune disorders, endocrine dysfunction, thrombophilia, life style factors, and maternal infections. However, the underlying causes remain undetermined in up to 50% of cases. In this clinical cohort study, we intended to get an epidemiological evidence for patients with recurrent spontaneous abortion associated with thrombophilla.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Woman who had 2 miscarriages before 12(th) week of gestation.Signed consent form.
排除标准
- •having experienced severe allergies, trauma history and/or operation history within 3 months;
- •with a history of mental illness and/or family history of mental illness
- •limb disabled
- •taking medicine within one month
- •suffering major events or having mood swings
- •with a history of recurrent pregnancy loss
- •having internal and surgical disease(after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine routine)
- •chromosome aberrations in anyone of the couple.
结局指标
主要结局
D-Dimer
时间窗: through study completion, an average of 3 year
次要结局
- platelet aggregation time(through study completion, an average of 3 year)
- BMI in kg/m^2(through study completion, an average of 3 year)
- anticardiolipin antibody(through study completion, an average of 3 year)
研究者
Shihua Bao
Principal Investigator
Shanghai First Maternity and Infant Hospital
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Risk Factors for Early Infant Colonization With Methicillin-Resistant Staphylococcus AureusMethicillin-resistant Staphylococcus AureusNCT01141101Boston Medical Center100
已完成
不适用
Epidemiology of SAIDs.Autoinflammatory DiseasesNCT03643809University Hospital, Montpellier500
Unknown
不适用
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in SepsisSepsisNCT04427371Jianfeng Xie100
已完成
不适用
PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)Multiple System Atrophy - Parkinsonian Subtype (MSA-P)Multiple System Atrophy - Cerebellar Subtype (MSA-C)NCT02035761University of Michigan23
招募中
不适用
RASopathy BiorepositoryRAS MutationNeurofibromatosis 1Noonan Syndrome With Multiple LentiginesNoonan Neurofibromatosis SyndromeCardiofaciocutaneous SyndromeCostello SyndromeLegius SyndromeSmith-Kingsmore SyndromeMTOR Gene MutationGATOR-1 Gene MutationSYNGAP1-Related Intellectual DisabilityDLG4MAPK1 Gene MutationNoonan SyndromeNCT04395495Children's Hospital Medical Center, Cincinnati1,000