Carotid Stenosis Management During the COVID-19 Era with Best Medical Intervention Alone (CASCOM Study): A prospective study of the rate of ipsilateral stroke in five risk-stratified cohorts of patients with at least 50% carotid artery stenosis

Monash University0 个研究点目标入组 1,543 人开始时间: 2021年11月25日最近更新: 2021年11月29日

适应症

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•i.Stroke or TIA patient with 50-99% carotid stenosis ipsilateral to the implicated brain region/eye or patient with 60-99% asymptomatic carotid stenosis (using 'NASCET' or 'NASCET' equivalent criteria to measure stenosis severity).
•ii.Age at least 18 years.
•iii.Willing and able to consent and be followed up for at least 24 months.
•iv.Life expectancy at least 24 months (therefore, a 9-Point Clinical Frailty Scale Score of 1-6).
•v.Absence of stroke resulting in severe deficit (mRS >3 and/or no useful function on either side of the body).
•vi.Absence of neurological, psychological or cognitive condition likely to impede recognition of cerebral or retinal stroke or TIA, including moderate or severe dementia, neurodegenerative disease with significant neurological impairment present or expected in the next 3 years).
•vii.Stenosis of study carotid artery attributable to atherosclerotic disease.
•viii.No previous ipsilateral carotid endarterectomy, carotid angioplasty or stenting, trans-carotid arterial revascularisation or other carotid artery procedure.

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