KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation (KNOW-KT)

• Conditions: Complications After Kidney Transplant; Kidney Transplant Recipients

• Registration Number: NCT02042963
• Lead Sponsor: Seoul National University Hospital

Brief Summary

KNOW-KT (KoreaN cohort study for Outcome in patients With KT: A 9-year Longitudinal cohort study of the Korean adult KT patients), funded by Korea Center for Disease Control and Prevention (KCDC) was established in 2012 by a group of transplant physicians, transplant surgeons, nephrologists, epidemiologists, and biostatisticians in Korea.

We aimed to establish an adult KT cohort, to investigate the renal allograft outcomes, mortality, complications, and to explore traditional or nontraditional risk factors for morbidity and mortality. We established a bio-bank to integrate clinical and biological information. Here, we report design and method of the KNOW-KT.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Status Verified: 2014-01
• Study First Submitted: 2014-01-20
• Study First Submitted QC: 2014-01-20
• Last Update Submitted: 2014-01-20
• Study First Posted: 2014-01-23
• Last Update Posted: 2014-01-23
• Primary Completion: 2021-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Recipients and Donors of kidney transplant

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Exclusion Criteria

• Multi-organ transplant recipients

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
overall mortality	9 years
Allograft survival	9 years	defined as re-transplant or initiation of maintenance dialysis

Secondary Outcome Measures

Name	Time	Method
cardiovascular event	9 years	Acute Myocardial Infarction Revascularization : PCI or CABG Stroke Admission from Congestive heart failure
Albuminuria	9 years
New onset of diabetes after transplant	9 years
Acute Rejection	9 years
Quality of Life	2 years

Trial Locations

Locations (1)

Seoul National Univeristy Hospital; 🇰🇷 Seoul, Korea, Republic of