The effects of sitaglibtin, glutazone and other glucose lowering drugs on inflammatory and coagulative factors and lipid profile in type 2 diabetes patients
Phase 3
Recruiting
- Conditions
- Type 2 diabetes.Type 2 diabetes mellitus with hyperosmolarity
- Registration Number
- IRCT20130610013612N9
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Age 45-55 years
HbA1C is more than 7 in less than 8.
BMI is greater than 25 and less than 30.
Exclusion Criteria
Having any cardiovascular, inflammatory, autoimmune disease
Taking warfarin
Presence of infection
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method High-Sensitivity C-Reactive Protein. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.;HDL Cholesterol. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.;Fibrogen. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.
- Secondary Outcome Measures
Name Time Method Fast blood sugar. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.;Cholestrol. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.;Triglyceride. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Blood Test.;Body Mass Index. Timepoint: Baseline and 3 months after the treatment. Method of measurement: Weigh.
Related Research Topics
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What molecular mechanisms underlie sitagliptin and glitazone effects on inflammation and coagulation in type 2 diabetes?
How does IRCT20130610013612N9 compare sitagliptin/glitazone to standard-of-care glucose-lowering agents for lipid and coagulation outcomes?
Which biomarkers predict response to DPP-4 inhibitors or PPAR-γ agonists in type 2 diabetes with hyperosmolarity?
What are the safety profiles of sitagliptin and glitazone in phase III trials for type 2 diabetes patients with hyperosmolarity?
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