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Clinical Trials/NL-OMON55817
NL-OMON55817
Recruiting
N/A

Prediction and recovery of cognitive impairment in neurosurgical patients. - Predict

Elisabeth-Tweesteden ziekenhuis0 sites1,230 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
Elisabeth-Tweesteden ziekenhuis
Enrollment
1230
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational non invasive

Investigators

Sponsor
Elisabeth-Tweesteden ziekenhuis

Eligibility Criteria

Inclusion Criteria

  • The study sample will be composed of patients admitted for intracranial
  • neurosurgical treatment of brain tumours (e.g., meningiomas, adenomas, gliomas
  • or metastases), vascular compression syndromes (e.g., trigeminal neuralgia) or
  • lesions (e.g., aneurysms)., Eligible subjects for the control group are:
  • 1\) sociodemographically similar to the patient group
  • 2\) in good health, with no current or past psychiatric, neurologic, or
  • cognitive disorder, and mediation\-use that interferes with cognitive function

Exclusion Criteria

  • Patients and Dutch control subjects will be excluded from participation in this
  • 1\) if lack basic proficiency in Dutch
  • 2\) if their IQ is below 85 or if they have low cognitive skills
  • 3\) if their Karnovsky Performance Scale is under 60
  • 4\) if they are completely unfamiliar with the use of computers
  • 5\) if they have an additional (history of) a significant neurological or
  • psychiatric disorder
  • 6\) if there is no surgery\-related complication (morbidity or mortality due to
  • e.g., thrombosis or heart attack)
  • \[APOE substudy: objection against 'further use' of samples of previously drawn

Outcomes

Primary Outcomes

Not specified

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