NL-OMON50619已完成不适用
DiabetEs Type 2 and thE Role of MacroalbumInuria; a diagnostic tool for vascular ageing with 18F-NaF PET/CT imaging - DETERMINE
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Inclusion criteria T2D patients:
- •* Men and women, age above 18 years
- •* Written informed consent
- •* Using RAAS inhibitors
- •* Fulfils ADA criteria for diabetes
- •o Fasting plasma glucose * 7.0 mmol/l OR
- •o Random plasma glucose * 11.1 mmol/l OR
- •o HbA1C * 6,5%, Inclusion criteria healthy controls:
- •* Men and women, age above 18 years
- •* Written informed consent
- •* eGFR above 60 ml/min/175m2 (CKD-EPI formula)
排除标准
- •Exclusion criteria T2D patients:
- •* Type 1 diabetes
- •* Clinically significant liver disease
- •* Other causes for macroalbuminuria than nephropathy
- •* Previous cardiovascular disease, defined as stable coronary artery disease or
- •acute coronary syndrome, stroke or transient ischemic attack, peripheral artery
- •* Patients who are mentally incompetent and cannot sign a Patient Informed
- •* Claustrophobia
- •* Pregnancy or breastfeeding women.
- •* Current active bone malignancy or in the previous 6 months
- •* Disorders affecting bone metabolism, e.g. hyperparathyroidism, Paget's disease
- •* Systolic blood pressure > 200 mmHg,
- •Exclusion criteria healthy controls:
- •* Type 1 or 2 diabetes
- •* Micro- or macroalbuminuria
- •* Clinically significant liver disease
- •* Previous cardiovascular disease, defined as stable coronary artery disease or
- •acute coronary syndrome, stroke or transient ischemic attack, peripheral artery
- •* Patients who are mentally incompetent and cannot sign a Patient Informed
- •* Claustrophobia
- •* Pregnancy or breastfeeding women.
- •* Current active bone malignancy or in the previous 6 months
- •* Disorders affecting bone metabolism, e.g. hyperparathyroidism, Paget's disease
- •* Systolic blood pressure > 200 mmHg
研究者
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