Correlation Between Ultrasonographic Fetal Soft Markers and Aneuploidy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To study the association between soft markers identified at second trimester ultrasound and aneuploidy.
研究概览
简要总结
The purpose of this study is to investigate the prevalence of soft markers which will be identified during a second trimester ultrasound. Secondary aims were to estimate the association between the soft markers and trisomies 13, 18 and 21 as well as the effect on the number of invasive tests will be performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •pregnant woman between (16-24) weeks of gestation.
- •singelton pregnancy.
排除标准
- •Multiple pregnancies.
- •Mental condition rendering the patients unable to understand the nature and scope of the study.
结局指标
主要结局
To study the association between soft markers identified at second trimester ultrasound and aneuploidy.
时间窗: 1 year
fetal soft markers detection which include the following: * choroid plexus cyst. * Mild ventriculomegaly. * Enlarged cistern magna. * Nasal bone hypoplasia. * Increased nuchal fold. * Echogenic cardiac focus. * Single umbilical artery. * Pyelectasis. * Echogenic bowl. * Short femur. * Short humerus. All data will be collected and statistics will be done for the correlation between one or more soft markers with structural anomalies and its relation with aneuploidy.
次要结局
未报告次要终点
研究者
Yasmin Ahmed Bassiouny
Assistant Professor
Cairo University