Pilot Study for the Effects of Transcranial Magnetic Stimulation on the Brain Using an Electronic Medical Device: A Single Institution, Randomized, Double-blind, Sham-controlled Study Using Multimodal Neuroimaging in Healthy Young Adults

Ewha Womans University Mokdong Hospital1 site in 1 country30 target enrollmentDecember 2016

ConditionsHealthy

Overview

Phase: N/A
Intervention: Not specified
Conditions: Healthy
Sponsor: Ewha Womans University Mokdong Hospital
Enrollment: 30
Locations: 1
Primary Endpoint: Metabolic brain changes in magnetic resonance imaging by computational approaches
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is a randomized, double-blind, and sham-controlled trial to examine the effects of transcranial magnetic stimulation on the brain of health individuals.

Detailed Description

The efficacy of repetitive transcranial magnetic stimulation on the brain will be assessed by multimodal neuroimaging in healthy individuals.

Registry

clinicaltrials.gov

Start Date

December 2016

End Date

November 2017

Last Updated

6 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Ewha Womans University Mokdong Hospital

Responsible Party

Principal Investigator

Sujung Yoon

Professor

Ewha Womans University Mokdong Hospital

Eligibility Criteria

Inclusion Criteria

•Aged 19-39 years
•Informed consent

Exclusion Criteria

•Pregnancy or breastfeeding
•High fever patient
•Current and past history of seizure or epilepsy
•Evidence of epilepsy on EEG
•Pregnancy or possibility of pregnancy during period
•Major medical or neurological illnesses
•Evidence of alcohol intake on alcohol breath test
•Contraindications to MRI scans and transcranial magnetic stimulation
•Risk of skin burns
•Use of medications that could have influenced on the study

Outcomes

Primary Outcomes

Metabolic brain changes in magnetic resonance imaging by computational approaches

Time Frame: after 5 sessions (1 session/day) equals 5 days

Secondary Outcomes

Standardized scores on a neuropsychological test battery(after 5 sessions (1 session/day) equals 5 days)
Functional brain changes in magnetic resonance imaging by computational approaches(after 5 sessions (1 session/day) equals 5 days)
Analysis of EEG activity(after 5 sessions (1 session/day) equals 5 days)