Evaluation of the Role of Genicular Nerve Block When Combined With Adductor Canal Block for Pain Control Following Knee Arthroscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- post-operative pain after 6 hours after the time of administration of the block according to VAS score.
研究概览
简要总结
The intervention tests the efficacy of Genicular nerve block when combined with Adductor canal block in comparison with Adductor canal block alone to control post operative pain in knee arthroscopy
详细描述
A. Preoperative settings:
All patients will be assessed preoperatively by careful history taking, full physical examination, and laboratory evaluation. An informed written consent will be taken from every patient just before the surgery.
Intraoperative and postoperative settings:
On arrival to the operating room, baseline parameters such as ECG, mean arterial blood pressure, heart rate, and oxygen saturation will be recorded. Intravenous line will be inserted, and IV Ringer's solution will be started, then induction of general anesthesia: Preoxygenation with 100% oxygen will be carried out for 2-3 minutes. Induction of anesthesia will be done using intravenous fentanyl 1-2 µg/kg and propofol 1-2 mg/kg. Endotracheal intubation will be facilitated with atracurium 0.4-0.5 mg/kg. Proper intubation will be confirmed by ETCO2 and bilateral auscultation of the chest. Anesthesia will be maintained with 60:40 oxygen mixed with air and isoflurane 1.2%. Lungs will be ventilated using volume-controlled ventilation with tidal volumes and respiratory rate adjusted to maintain end tidal CO2 at 35-40 MMGH.
After induction of general anesthesia and intubation:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Physical status: ASA 1 or 2 and candidates for knee arthroscopy.
- •Age group: 18-50 years.
- •No sex predilection.
排除标准
- •Physical status: ASA III or above.
- •Patients with a history of drug allergies to study drugs.
- •Previous trauma or surgery to the leg.
- •Opioids or alcohol abuse.
- •Bleeding tendency.
- •Dysesthesia, loss of sensation around the knee or medial aspect of the thigh.
- •Inability to cooperate.
研究组 & 干预措施
Adductor canal block (ACB) only
This group will receive Adductor canal block only (control group)
干预措施: Adductor Canal Block (ACB) Only (Procedure)
Adductor canal block (ACB) combined with Genicular nerve block (GNB)
This group will receive Adductor canal block and Genicular nerve block
干预措施: Adductor canal block (ACB) combined with Genicular nerve block (GNB) (Procedure)
结局指标
主要结局
post-operative pain after 6 hours after the time of administration of the block according to VAS score.
时间窗: During 24 hours
* To assess postoperative pain and its intensity a segmented numeric version of the visual analogue scale (VAS) is the score that used. The patient will select a whole number (0- 10 integers) that best reflects the intensity of his pain; 1-10 is recorded by a blinded investigator during 24 hours * All patients receive intravenous paracetamol IV/8 hours, Patients receive intravenous pethidine 0.5mg/kg as rescue analgesia when the VAS is equal or more than 4.
次要结局
未报告次要终点