Effect of probiotic supplementation in patients with type 2 diabetes
- Conditions
- Type 2 diabetes mellitus.diabetes (mellitus)(nonobese)(obese): adult-onsetmaturity-onset nonketotic stable non-insulin-dependent diabetes of the young
- Registration Number
- IRCT20090901002394N44
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 84
Willing to participate and signing informed consent
Having type 2 diabetes based on medical records
At least 2 years history of type 2 diabetes
No change in the type and dose of medication taken 8 weeks before the intervention
Age 45-65
Not eating probiotic-containing foods for the past 4 weeks
Cancer, severe liver and kidney disorders, heart failure and surgery and other endocrine disorders
Pregnancy and lactation and hormone-sensitive conditions
Use of liver, anticoagulant, and platelet-degrading drugs
Use of antidepressants and other drugs that affect the nerves
Insulin injection
Contraceptive use
Recent dietary supplements (no case if calcium - vitamin D and group B supplements are routinely consumed for the past 6 months)
Use of antibiotics for the past 1 month
Tobacco, drugs and alcohol
weight loss diet and weight changes over 5% in the last 3 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive function. Timepoint: at baseline, and after 2 month. Method of measurement: Addenbrooke’s Cognitive Examination - Trail Making Test.;BDNF. Timepoint: at baseline, and after 2 month. Method of measurement: Eliza.
- Secondary Outcome Measures
Name Time Method Physical activity. Timepoint: beginning and end of intervention. Method of measurement: IPAQ questionnaire.;Energy intake. Timepoint: beginning and end of intervention. Method of measurement: Three-day food record.