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Clinical Trials/NCT03808363
NCT03808363
Completed
N/A

High-intensity Interval Training Versus Moderate Intensity Continuous Training as a Means to Improve Cardiometabolic Health After Spinal Cord Injury

Brock University1 site in 1 country8 target enrollmentFebruary 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Metabolic Syndrome
Sponsor
Brock University
Enrollment
8
Locations
1
Primary Endpoint
Waist circumference (inches)
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Testing the efficacy of high intensity interval training (HIIT), as compared to current research supporting moderate intensity continuous training (MICT), as a means to improve cardiometabolic health after spinal cord injury.

Detailed Description

This study aims to challenge the effectiveness of the current aerobic exercise recommendations for individuals with spinal cord injuries (SCI). Currently, moderate intensity continuous training (MICT) is suggested however this study intends to explore the effectiveness of high intensity interval training (HIIT). To do so, approximately 8 individuals with SCI will be undergo a 6 week HIIT intervention consisting of 3 sessions per week. With a focus on cardiometabolic health markers (listed in outcome measure section), we aim to provide support for HIIT as a viable method of mitigating cardiovascular risk in a SCI population.

Registry
clinicaltrials.gov
Start Date
February 1, 2019
End Date
December 15, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

David Ditor

David Ditor, PhD - Professor, Kinesiology

Brock University

Eligibility Criteria

Inclusion Criteria

  • Individuals with a spinal cord injury (paraplegia or tetraplegia, complete or incomplete) who are at least one-year post injury.
  • Declared medically stable, and able to communicate clearly in English.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Waist circumference (inches)

Time Frame: 6 weeks

Central adiposity will be measured by tape measure to monitor possible weight loss

Cholesterol

Time Frame: 6 weeks

Total and HDL cholesterol will be measured in serum

Triglycerides

Time Frame: 6 weeks

Triglycerides will be measured in serum

Glycated Hemoglobin (HbA1c)

Time Frame: 6 weeks

Glycated hemoglobin will be measured in whole blood as an indicator of diabetic risk

Tumor necrosis factor (TNF-a)

Time Frame: 6 weeks

TNF-a will be used as an inflammatory representative and will be measured in serum

Interleukin - 10 (IL-10)

Time Frame: 6 weeks

IL-10 will will be used as an anti-inflammatory representative and will be measured in serum

Pulse Wave Velocity

Time Frame: 6 weeks

Arterial stiffness, a common measure for cardiac risk will be measured

Adiponectin

Time Frame: 6 weeks

Adiponectin will will be used as a surrogate for insulin resistance and will be measured in serum

Blood pressure

Time Frame: 6 weeks

Measured through a digital cuff, the focus will be on both systolic and diastolic

Peak Oxygen Consumption (VO2 peak)

Time Frame: 6 weeks

VO2 peak will be measured by a Moxus metabolic cart to determine changes in fitness

C Reactive Protein (CRP)

Time Frame: 6 weeks

CRP will will be used as an inflammatory representative and will be measured in serum

Leptin

Time Frame: 6 weeks

Leptin will will be used as a body fat representative and will be measured in serum

Secondary Outcomes

  • Physical Activity Enjoyment Scale (PACES)(6 weeks)

Study Sites (1)

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