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临床试验/NCT03808363
NCT03808363已完成不适用

High-intensity Interval Training Versus Moderate Intensity Continuous Training as a Means to Improve Cardiometabolic Health After Spinal Cord Injury

Brock University1 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2019年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
8
试验地点
1
主要终点
Waist circumference (inches)

研究概览

简要总结

Testing the efficacy of high intensity interval training (HIIT), as compared to current research supporting moderate intensity continuous training (MICT), as a means to improve cardiometabolic health after spinal cord injury.

详细描述

This study aims to challenge the effectiveness of the current aerobic exercise recommendations for individuals with spinal cord injuries (SCI). Currently, moderate intensity continuous training (MICT) is suggested however this study intends to explore the effectiveness of high intensity interval training (HIIT). To do so, approximately 8 individuals with SCI will be undergo a 6 week HIIT intervention consisting of 3 sessions per week. With a focus on cardiometabolic health markers (listed in outcome measure section), we aim to provide support for HIIT as a viable method of mitigating cardiovascular risk in a SCI population.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Individuals with a spinal cord injury (paraplegia or tetraplegia, complete or incomplete) who are at least one-year post injury.
  • Declared medically stable, and able to communicate clearly in English.

排除标准

  • 未提供

结局指标

主要结局

Waist circumference (inches)

时间窗: 6 weeks

Central adiposity will be measured by tape measure to monitor possible weight loss

Cholesterol

时间窗: 6 weeks

Total and HDL cholesterol will be measured in serum

Triglycerides

时间窗: 6 weeks

Triglycerides will be measured in serum

Glycated Hemoglobin (HbA1c)

时间窗: 6 weeks

Glycated hemoglobin will be measured in whole blood as an indicator of diabetic risk

Tumor necrosis factor (TNF-a)

时间窗: 6 weeks

TNF-a will be used as an inflammatory representative and will be measured in serum

Interleukin - 10 (IL-10)

时间窗: 6 weeks

IL-10 will will be used as an anti-inflammatory representative and will be measured in serum

Pulse Wave Velocity

时间窗: 6 weeks

Arterial stiffness, a common measure for cardiac risk will be measured

Adiponectin

时间窗: 6 weeks

Adiponectin will will be used as a surrogate for insulin resistance and will be measured in serum

Blood pressure

时间窗: 6 weeks

Measured through a digital cuff, the focus will be on both systolic and diastolic

Peak Oxygen Consumption (VO2 peak)

时间窗: 6 weeks

VO2 peak will be measured by a Moxus metabolic cart to determine changes in fitness

C Reactive Protein (CRP)

时间窗: 6 weeks

CRP will will be used as an inflammatory representative and will be measured in serum

Leptin

时间窗: 6 weeks

Leptin will will be used as a body fat representative and will be measured in serum

次要结局

  • Physical Activity Enjoyment Scale (PACES)(6 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

David Ditor

David Ditor, PhD - Professor, Kinesiology

Brock University

研究点 (1)

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