Effect of Volume Increase Compared to Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success in Cases With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- 1.8 ml mepivacaine hydrochloride
- Conditions
- Symptomatic Irreversible Pulpitis
- Sponsor
- Cairo University
- Enrollment
- 75
- Primary Endpoint
- Anesthetic success
- Last Updated
- 4 years ago
Overview
Brief Summary
To assess the anesthetic success of inferior alveolar nerve block (IANB), intraoperative pain intensity and need for supplemental anesthesia on administration of 1.8ml or 3.6ml 2% mepivacaine IANB, or 1.8ml 2% mepivacaine IANB plus 1.8ml 4% articaine buccal infiltration (BI) in mandibular molars with symptomatic irreversible pulpitis.
Detailed Description
Patients with moderate-to-severe preoperative pain related to mandibular molars with symptomatic irreversible pulpitis will be included. Patients receive 1.8 ml, 3.6 ml 2% mepivacaine IANB, or 1.8ml 2% mepivacaine IANB plus 1.8ml 4% articaine BI. Anesthetic success of inferior alveolar nerve block, intraoperative pain intensity and need for supplemental anesthesia will be assessed during treatment.
Investigators
Reham Anwar Mohammed El Said Sleem
Ms
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Patients in good health (ASA Class I, II).
- •Age between 18-60 years old.
- •Males or females.
- •Mandibular molar teeth diagnosed with symptomatic irreversible pulpitis.
- •Patients who can understand NRS scale and sign the informed consent.
Exclusion Criteria
- •Patients who had used any type of analgesic medication during the preceding 8 hours before the treatment.
- •Pregnant or nursing females.
- •Patients with a contraindication for the use of mepivacaine, articaine or any used drug or material.
Arms & Interventions
1.8 ml mepivacaine IANB
Intervention: 1.8 ml mepivacaine hydrochloride
3.6 ml mepivacaine IANB
Intervention: 3.6 ml mepivacaine hydrochloride
1.8 ml mepivacaine IANB plus 1.8 ml articaine BI
Intervention: 1.8 ml mepivacaine hydrochloride IANB plus 1.8 ml articaine hydrochloride BI
Outcomes
Primary Outcomes
Anesthetic success
Time Frame: During the treatment
Will be recorded by 11-point numerical rating scale (NRS) consisting of numbers from 0 through 10. 0: reading represents "no pain" 1-3 : readings represent "mild pain" 4-6 : readings represent "moderate pain" 7-10 : readings represent "severe pain". Success will be defined as no to mild pain.
Secondary Outcomes
- Intraoperative pain(During the treatment)
- Need for supplemental anesthesia(During the treatment)