Effect of Volume Increase Compared to Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success in Cases With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 75
- 主要终点
- Anesthetic success
研究概览
简要总结
To assess the anesthetic success of inferior alveolar nerve block (IANB), intraoperative pain intensity and need for supplemental anesthesia on administration of 1.8ml or 3.6ml 2% mepivacaine IANB, or 1.8ml 2% mepivacaine IANB plus 1.8ml 4% articaine buccal infiltration (BI) in mandibular molars with symptomatic irreversible pulpitis.
详细描述
Patients with moderate-to-severe preoperative pain related to mandibular molars with symptomatic irreversible pulpitis will be included. Patients receive 1.8 ml, 3.6 ml 2% mepivacaine IANB, or 1.8ml 2% mepivacaine IANB plus 1.8ml 4% articaine BI. Anesthetic success of inferior alveolar nerve block, intraoperative pain intensity and need for supplemental anesthesia will be assessed during treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients in good health (ASA Class I, II).
- •Age between 18-60 years old.
- •Males or females.
- •Mandibular molar teeth diagnosed with symptomatic irreversible pulpitis.
- •Patients who can understand NRS scale and sign the informed consent.
排除标准
- •Patients who had used any type of analgesic medication during the preceding 8 hours before the treatment.
- •Pregnant or nursing females.
- •Patients with a contraindication for the use of mepivacaine, articaine or any used drug or material.
研究组 & 干预措施
1.8 ml mepivacaine IANB
干预措施: 1.8 ml mepivacaine hydrochloride (Drug)
3.6 ml mepivacaine IANB
干预措施: 3.6 ml mepivacaine hydrochloride (Drug)
1.8 ml mepivacaine IANB plus 1.8 ml articaine BI
干预措施: 1.8 ml mepivacaine hydrochloride IANB plus 1.8 ml articaine hydrochloride BI (Drug)
结局指标
主要结局
Anesthetic success
时间窗: During the treatment
Will be recorded by 11-point numerical rating scale (NRS) consisting of numbers from 0 through 10. 0: reading represents "no pain" 1-3 : readings represent "mild pain" 4-6 : readings represent "moderate pain" 7-10 : readings represent "severe pain". Success will be defined as no to mild pain.
次要结局
- Intraoperative pain(During the treatment)
- Need for supplemental anesthesia(During the treatment)
研究者
Reham Anwar Mohammed El Said Sleem
Ms
Cairo University