Skip to main content
Clinical Trials/NCT02884596
NCT02884596
Completed
Not Applicable

Anesthetic Success of Inferior Alveolar Nerve Block for Mandibular Molars With Symptomatic Irreversible Pulpitis in Women Taking Selective Serotonin Reuptake Inhibitors

Isfahan University of Medical Sciences1 site in 1 country90 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Local Anesthesia
Sponsor
Isfahan University of Medical Sciences
Enrollment
90
Locations
1
Primary Endpoint
the success rate of the IAN block
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

To evaluate the success of inferior alveolar nerve block (IANB) for mandibular molars with irreversible pulpitis in women under treatment with selective serotonin reuptake inhibitors (SSRIs).

Detailed Description

Seventy patients with a diagnosis of symptomatic irreversible pulpitis in one mandibular molar were assigned to either SSRI users or SSRI non-users groups. SSRIs users were 45 women who take SSRIs referred for endodontic treatment from a psychiatric clinic to the clinic of the endodontic department of Isfahan University of Medical Sciences. SSRIs non-users were 45 women who did not take SSRIs referred for endodontic treatment to the same dental clinic. The protocol of the study was approved by the Ethics Committee of the university (no. 394867). Written informed consent was obtained from all the patients. The level of anxiety of the patients was determined by using the Corah Dental Anxiety Scale. The patients registered their baseline pain severity using a Heft-Parker visual analogue scale (HP-VAS). Two standard IANBs (1.8-mL cartridges) of 2% lidocaine with 1:100,000 epinephrine (Darupakhsh, Tehran, Iran) were administered to each patient. Fifteen minutes after injection, the teeth were isolated. Access cavity preparation was started. The patients was instructed by the same operator to mark his or her pain experienced during the access cavity preparation.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
March 2016
Last Updated
7 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Masoud Saatchi, DDS MSc

Professor of Endodontics, School of Dentistry, Isfahan University of Medical Sciences

Isfahan University of Medical Sciences

Eligibility Criteria

Inclusion Criteria

  • vital mandibular molar tooth
  • diagnosis of symptomatic irreversible pulpitis

Exclusion Criteria

  • younger than 18 years old
  • history of significant medical conditions
  • allergies to local anesthetics or sulfites
  • pregnancy
  • active sites of pathosis in area of injection
  • inability to give informed consent

Outcomes

Primary Outcomes

the success rate of the IAN block

Time Frame: taking any type of SSRI for at least six weeks prior to the study

Study Sites (1)

Loading locations...

Similar Trials