Hyperspectral Imaging for the evaluation of microcirculatory response in patients following cardiopulmonary bypass.

Completed

• Conditions: R57; I25; Shock, not elsewhere classified; Chronic ischaemic heart disease

• Registration Number: DRKS00030519
• Lead Sponsor: niveristätsklinikum Essen, AöR Klinik für Anästhesiologie und Intensivmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-10
• Study Completion: 2023-03-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Written declaration of consent by the study participant

- Age >18 years

- Elective cardiac surgery using a cardiopulmonary bypass (heart-lung machine)

Exclusion Criteria

- Age < 18 years
- Refusal to participate in studies
- Known pregnancy
- Dark skin type (methodological limitation for cutaneous hyperspectral imaging)
- Emergency intervention
- Aortic surgery (micro- and macrocirculation often already influenced by the disease itself)
- Presence of Extracorporeal Life Support (ECLS) systems assuming hemodynamic functions (vv/vaECMO, Impella, IABP, LVAD) at the time of inclusion

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcomes are the correlation of the HSI parameters with the vasoactive-inotropic score (VIS). The VIS quantifies the amount of cardiovascular support and includes the active substances dopamine, dobutamine, epinephrine, milrinon, vasopressin and norepinephrine. The primary outcome parameters are the correlations between the HSI parameters (StO2, NIR or NPI, THI and TWI) after a VOT induced PORH as expression of the cutaneous MRF and the VIS.

Secondary Outcome Measures

Name	Time	Method
The secondary outcomes are derived from the secondary goals and include the care data collected as part of standard anaesthesiological therapy.