Hyperspectral imaging for the evaluation of microcirculatory alterations in perioperative intensive care medicine

• Conditions: R57.2; Shock, not elsewhere classified; R57; Septic shock

• Registration Number: DRKS00017313
• Lead Sponsor: Klinik für Anästhesiologie, Universitätsklinikum Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-05
• Study Completion: 2020-10-16
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

All patients: -written consent to participate -Age = 18 Jahre

Groups with Sepsis/ septic shock:
-suspected infection
-SOFA-Score = 2

Group undergoing pancreatic surgery:
- planned admission to intensive care ward
-open pancreatic resection

healthy respondents:
- ASA 1 or ASA 2 Status

Exclusion Criteria

-refusal to participate
-Default of inclusion criteria
-preoperative diagnosis of atrial fibrillation in pancreatic surgery patients

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
-hyperspectral measurement of microcirculatory parameters on different Skin Areas ( Hand, knee, ear)<br>-Evaluation of microcirculatory parameters under therapy according to Guidelines<br>-correlation of microcirculatory Parameters with morbidity and mortality (SOFA-score) in septic patients

Secondary Outcome Measures

Name	Time	Method
-association between heart-rate variability, butyrylcholine-activity and hyperspectral parameters<br>-correlation of microcirculatory parameters with inflammatory biomarkers