Study to compare two methods for measuring iv fluid requirement during Renal transplant recipient surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: N186- End stage renal disease
- Registration Number
- CTRI/2022/07/044142
- Lead Sponsor
- Tapas Kumar SIngh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 46
Inclusion Criteria
1.Age : 18 -60 years,
2.Living donor
3.ASA III
4. Undergoing renal transplant under general anaesthesia
5.Informed written consent
6.Easy sonoanatomy for IVC visualisation.
7.No or Less than 500 ml urine output per day
Exclusion Criteria
1.Impaired RV/LV function and ejection fraction or any ischaemic or other structural heart diseases
2.Morbid obesity,
3.Any lesion obscuring sonoanatomy
4.ABO incompatible
5.Central monitoring site other than Superior vena cava
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total fluid given in intraoperative period before kidney reperfusionTimepoint: at time just before clamp opening in both groups.
- Secondary Outcome Measures
Name Time Method Baseline and after surgery P/F ratiosTimepoint: end of surgery;Correlation between IVC distensibility and CVP valuesTimepoint: after intubation & CVP insertion <br/ ><br>after kidney bed is ready <br/ ><br>after skin closure;Day 1 and 2 Urine outputTimepoint: end of POD1 and POD 2;Difference in preoperative and post-operative lactate levels and Standard Base Excess in arterial blood gasTimepoint: end of surgery;Fall in creatinine levels till day 5Timepoint: end of POD5;Incidence of acute rejection in 3 months follow upTimepoint: end of three months;Incidence of breathlessness in postoperative periodTimepoint: end of POD1;Max fall in Mean Arterial pressures in one minute post clamp openingTimepoint: at the time of clamp opening;Total Noradrenaline used in intra operative periodTimepoint: at the end of surgery;Use of other vasopressors or inotropes other noradrenalineTimepoint: end of surgery