Validation of ACS NSQIP Risk Calculator for Predicting Complications After Thoracic Surgery at University Hospital Basel

Completed

• Conditions: Thoracic

• Registration Number: NCT06483464
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

This single-center retrospective research project aims to evaluate whether and what is the significance of the National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP) risk score in thoracic surgery at the University Hospital Basel.

Detailed Description

Advances in medical and surgical therapies have enabled treatment for polymorbid patients, who often have multiple chronic conditions. This has increased the need to accurately assess the risks of postoperative complications and mortality. Due to their complex health status, these patients are more susceptible to adverse outcomes following surgery, necessitating precise risk prediction to guide clinical decision-making and optimize outcomes.

This single-center retrospective research project compares the preoperative risk assessments by the National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP) risk calculator with actual complications (graded according to the Clavien-Dindo classification) observed in patients who underwent thoracic surgery at the University Hospital Basel between May 1, 2021, and March 1, 2022.

The ACS NSQIP risk calculator, a web-based tool, uses 21 preoperative risk factors to predict 13 perioperative outcomes, including serious complications, infections, and mortality. By evaluating these predictions against real patient outcomes, this research project aims to validate the calculator's accuracy specifically in the context of thoracic surgery.

The results of this research project could optimize patient care by better identifying high-risk patients and improving preoperative preparation.

Study Timeline

• Study Start: 2021-05-01
• Primary Completion: 2022-03-01
• Study Completion: 2023-08-31
• Status Verified: 2024-06
• Study First Submitted: 2024-06-21
• Study First Submitted QC: 2024-06-27
• Last Update Submitted: 2024-06-27
• Study First Posted: 2024-07-03
• Last Update Posted: 2024-07-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Patients with signed general research consent
• Patients who underwent surgery in our department for the period from 01.05.2021 to 01.03.2022
• Patients with preoperative ACS NSQIP Risk score

Exclusion Criteria

• Patients who have clearly stated that they would not agree in providing their clinical data for scientific purposes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Suitability of the ACS NSQIP risk calculator	Up to 30 days after surgery	To evaluate the suitability of the National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP) risk calculator for thoracic surgery, the ACS NSQIP risk score is compared to actual complications.; ACS NSQIP risk score is a tool used to predict the likelihood of postoperative complications and mortality in surgical patients. It is calculated based on a range of preoperative variables, including patient demographics, comorbidities, and the type of surgery being performed. The values of the ACS NSQIP risk score can range from 0 to 100, with higher scores indicating a higher risk of complications and a worse expected outcome.

Trial Locations

Locations (1)

Department of Thoracic Surgery, University Hospital of Basel; 🇨🇭 Basel, Switzerland