Study about deficiency of thyroid hormones following removal of larynx in laryngeal cancers
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2018/12/016652
- Lead Sponsor
- DR Architha Menon P
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 42
Inclusion Criteria
Patients with primary cancer of larynx and hypopharynx undergoing total laryngectomy/laryngopharyngectomy with hemithyroidectomy
Patients undergoing radiotherapy post laryngectomy
Exclusion Criteria
Patients with preoperative thyroid disease.
Patients with second primary or those who received radiotherapy prior to surgery for any cause.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the incidence of hypothyroidism and hypoparthyroidismTimepoint: Before surgery <br/ ><br>1 week post surgery <br/ ><br>6weeks post surgery <br/ ><br>4weeks post radiation
- Secondary Outcome Measures
Name Time Method Helps to assess subclinical and clinical hypothyroidism and hypoparathyroidism and treatment can be commenced as early as possible. Hence improves the lifestyle and general well being of the patientTimepoint: Before surgery <br/ ><br>1 week post surgery <br/ ><br>6weeks post surgery <br/ ><br>4weeks post radiation