Assessing The Effects Of Mild And Moderate Hypothermia On The Cerebral Oxymetery In Acyanotic Congenital Heart Disease Under The Cardiopulmonary Bypass

Not Applicable

Conditions: Congenital Acyanotic heart disease.

Registration Number: IRCT20201217049741N1

Lead Sponsor: Shahid Rajaei Heart Hospital, Tehran

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 64

Inclusion Criteria

Children 1 day to 14 years old undergoing surgery for Acyanotic congenital heart disease with pulmonary heart bypass
Children weighing 5 to 20 kg
No history of neurological diseases
No hepatic or renal insufficiency (creatinine above 2 mg / dL)
No preoperative anemia
No history of preoperative cardiopulmonary resuscitation
Parents' consent to participate in the research project

Exclusion Criteria

Hemodynamic instability
Emergency heart surgery
Lower the temperature during operation to below the desired temperature

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral oxygenation. Timepoint: 1- At the time after induction of anesthesia (baseline value), 2- At the time of cooling up to 34 degrees Celsius, 3- At the lowest level of cooling (first group 32 degrees Celsius), (second group 28 degrees Celsius), 4 - At the time of reheating (above 34 degrees Celsius), 5-after CPB. Method of measurement: Based on the amount of INVOS.;Blood lactate. Timepoint: 1- At the time after induction of anesthesia (baseline value), 2- At the time of cooling up to 34 degrees Celsius, 3- At the lowest level of cooling (first group 32 degrees Celsius), (second group 28 degrees Celsius), 4 - At the time of reheating (above 34 degrees Celsius), 5-after CPB. Method of measurement: Laboratory kits.;Incidence of neurological complications. Timepoint: From postoperative time to discharge. Method of measurement: Based on patient records.;Average intubation time. Timepoint: From the time of surgery to Extubation. Method of measurement: Based on patient records.

Secondary Outcome Measures