Comparison effect of religious cognitive- behavioral therapy, classic cognitive behavioral therapy and Sertraline on anxiety, depression, related bio markers and quality of life in post coronary artery bypass surgery Patients

Not Applicable

• Conditions: Anxiety, Depression, related biomarkers, Quality of life.; Organic anxiety disorder,Depressive episode; F06.4,F32

• Registration Number: IRCT201404122898N5
• Lead Sponsor: Mazandaran university of medical sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

The inclusion criteria include first-time coronary artery bypass, age of less than 65 years, and four weeks passing from their surgery. In addition, they shouldn’t have some mental disorders such as schizophrenia, bipolar disorder, and serious thoughts of suicide according to clinical interview (DSM-IV) that will be done by a psychiatrist. Obtaining the score of 8 or more in depression and anxiety based on HADS questionnaire. They shouldn’t suffer from mental or physical disease that prevents them from taking part in the therapy meetings. They should be able to communicate and speak in Farsi with, at least, junior high school education level .They should get the score of 25 and more in the Golriz and Baraheni’s religious attitude measure questionnaire.The exclusion criteria include: patients who receive Sertraline or other anti anxiety and anti depression drugs, patients who have previously attended the religious cognitive-behavioral therapy and classic cognitive-behavioral therapy courses.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire ( HADS ).;Depression. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire (HADS ).

Secondary Outcome Measures

Name	Time	Method
Improving the quality of life. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: SF-36 questionnair.;To become normal level of biomarkers( ?L6 ??L10 ? DHEA ?cortisol ? TNFa). Timepoint: before intervention ,3and 12 month after intervention. Method of measurement: ELISA.