The effect of religious cognitive- behavioral therapy ,classic cognitive- behavioral therapy and Citalopram on anxiety, depression , related biomarkers and quality of life of breast cancer patients.

Not Applicable

• Conditions: Anxiety, Depression, related biomarkres, Quality of life.; Organic anxiety disorder,Depressive episode; F06.4 ,F32

• Registration Number: IRCT201403042898N4
• Lead Sponsor: Mazandaran university of medical sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

Women with breast cancer who referring to Tuba Clinic for follow up, aged 18-65, being at stages 1 and 2, and having undergone surgery, chemotherapy, or radiotherapy,being able to communicate, speak Farsi, and having an education level of higher than junior high school, obtaining the score of 8 or more in depression and anxiety based on HADS questionnaire,no evidence of psychiatric disorders including schizophrenia, bipolar, and serious suicide thoughts based on the clinical interview (DSM-IV) that will be done by a psychiatrist, no evidence of severe physical conditions ( other malignancies ) preventing them from attending the treatment sessions , getting the score of 25 and more from Golriz and Baraheni’s religious attitude questionnaire,
Exclusion criteria:Having the experience of taking part in religious cognitive- behavioral therapy or classic cognitive- behavioral therapy courses and taking Citalopram or other drugs in the routine treatment due to their psychological problems at least two weeks ago.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire(HADS).;Depression. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: Hospital Anxiety Deprestion Questionnaire (HADS).

Secondary Outcome Measures

Name	Time	Method
Improving the quality of life. Timepoint: Before intervention ,3,6,9 and 12 month after intervention. Method of measurement: BR-23 , EORTCQLQ-C30 questionnaire.;To become normal level of biomarkers( ?L6 ??L10 ? DHEA ?cortisol ? IFN? ? TNFa). Timepoint: Before intervention ,3and 12 month after intervention. Method of measurement: ELISA.