Adaptive Image-Guided Radiotherapy (IGRT) for lung cancer using repeat treatment planning CT scan and PET-CT scans.

• Conditions: cancer of the airways; lung cancer; 10029107

• Registration Number: NL-OMON30265
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Eligible patients who will undergo a 4DCT or 4DCT-PET planning scan, and in whom (i) a pre-treatment GTV can be identified and (ii) will receive a minimum dose of 46 Gy in 4 weeks

Exclusion Criteria

Patients who will be irradiated after a complete response to chemotherapy or after a complete surgical resection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1.To establish the proportion of patients in whom an initial radiotherapy plan<br /><br>does not provide similar or improved coverage on a repeat planning procedure<br /><br>after 15 fractions.<br /><br>2. To indentify the characteristics of this sub-population of patients and<br /><br>design adaptiveimaging protocols to account for time trends.<br /><br>3. Establish the magnitude of reduction in toxicity risk to lung and esophagus<br /><br>in patients for whom reductions in PTV are possible</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>