Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- changes of retinal and choroidal thickness after hemodialysis
研究概览
简要总结
To evaluate the effect of hemodialysis on various ophthalmologic parameters in patients with end-stage kidney disease (ESRD).
详细描述
Subjects: patients with ESRD undergoing hemodialysis at the Dialysis Center of Hanyang Guri Hospital
Ocular parameters: visual acuity, intraocular pressure, axial length, OCT Other systemic parameters: body weight, ultrafiltration volume, and systolic/diastolic blood pressure
All measurements were performed near the dialysis center. Measurements were performed on Monday (for patients who underwent dialysis sessions on Monday, Wednesday, and Friday) or Tuesday (for patients who underwent dialysis sessions on Tuesday, Thursday, and Saturday.
All parameters were measured before and after the hemodialysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who are regularly dialyzed in our dialysis room to participate in the study
- •patients who agree with our study protocol
- •patients who have unstable general condition
排除标准
- •previous intraocular surgery, (2) baseline IOP greater than 22 mmHg, (3) presence of glaucomatous optic disc changes including excavation, thinning, or notching of the neuroretinal rim, (4) axial length greater than 26 mm, and (5) combined macular and retinal diseases such as central serous chorioretinopathy and age-related macular degeneration, except diabetic retinopathy.
结局指标
主要结局
changes of retinal and choroidal thickness after hemodialysis
时间窗: immediately (within 10 minutes) before and after hemodialysis
retinal \& choroidal thickness on OCT
次要结局
- the effect of hemodialysis (HD) on anterior chamber angle by anterior segment optical coherence(immediately (within 10 minutes) before and after hemodialysis)
- changes of foveal vascular density using optical coherence tomography-angiography (OCTA) after hemodialysis(immediately (within 10 minutes) before and after hemodialysis)
研究者
Yong Un shin
Assistant professor
Hanyang University