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临床试验/NCT04954482
NCT04954482已完成不适用

Anatomical and Biomechanical Study of Combined Reconstruction in the Treatment of III° Posterior Cruciate Ligament Injury

Peking University Third Hospital1 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2017年4月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
1
主要终点
The distance of posterior displacement of the tibia

研究概览

简要总结

To establish a III°PCL injury model on fresh cadaver knee specimens, and to define the pathological and anatomical connotation of III°PCL injury by using anatomical methods.

To explore and establish combined reconstruction techniques, including PCL reconstruction combined with injury repair and reconstruction, and to explore the role of combined reconstruction techniques in maintaining knee stability through biomechanical experiments.

详细描述

Objective: (1) To establish a III°PCL injury model on fresh cadaver knee specimens, and to define the pathological and anatomical connotation of III°PCL injury by using anatomical methods.

(2) To explore and establish combined reconstruction techniques, including PCL reconstruction combined with injury repair and reconstruction, and to explore the role of combined reconstruction techniques in maintaining knee stability through biomechanical experiments.

Design: ① The subjects of this study were fresh cadaver knee specimens.

  • Sample size:

A Anatomical study of injury model, planning 6 cases. B. Exploration of treatment methods for complicated injuries. 8 cases of specimens are planned to be used. According to the pathological and anatomical content of III°PCL injury (IKDC standard), the repair and reconstruction techniques of combined injury were designed. Arthroscopic transtibial single-bundle PCL reconstruction technique was used in all the reconstruction of PCL. Using the robotic arm or universal sensor test system as the biomechanical test platform, Biomechanical tests were carried out on the experimental specimens, and the results were compared to determine the shortcomings of the new PCL reconstruction, according to which the surgical procedures were improved, and then the biomechanical tests were carried out. After repeated technical improvement (4 cycles, 2 specimens per cycle), the new PCL reconstruction technique was finally determined.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • no sports injuries such as knee ligament rupture and meniscus injury specimens

排除标准

  • sports injuries such as knee ligament rupture and meniscus injury specimens

结局指标

主要结局

The distance of posterior displacement of the tibia

时间窗: On the day of enrollment.

The robotic arm/universal sensor test system was used as the test platform to test the specimens .

次要结局

  • Tibial valgus Angle(On the day of enrollment.)
  • Internal rotation angle of the tibia(On the day of enrollment.)
  • External rotation angle of the tibia(On the day of enrollment.)
  • Tibia varus Angle(On the day of enrollment.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Liu Ping

chief physician

Peking University Third Hospital

研究点 (1)

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