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Clinical Trials/NCT01714492
NCT01714492
Completed
N/A

In Vivo Mechanics Analysis of Patients Having a Sigma Mobile Bearing TKA

The University of Tennessee, Knoxville3 sites in 1 country8 target enrollmentApril 2012

Overview

Phase
N/A
Intervention
Not specified
Conditions
Knee Prosthesis
Sponsor
The University of Tennessee, Knoxville
Enrollment
8
Locations
3
Primary Endpoint
Range of Motion During Flexion of Deep Knee Bend Activity
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Utilize previously developed mathematical model to determine in vivo knee mechanics (kinematics, forces, stresses, areas and sound) for subjects having a Sigma Posterior Stabilizing (PS) mobile bearing (MB) total knee arthroplasty (TKA). There are several hypotheses for this study, although the most prominent is: Subjects having a Sigma RP PS TKA will experience polyethylene bearing rotation at 10 years post-operative, similar to their previous evaluations at six months, two years and five years.

Detailed Description

Additional hypotheses: * Subjects having a Sigma RP PS TKA will experience full ideal femorotibial contact mechanics. * Subjects having a Sigma RP PS TKA will experience optimal cam/post mechanics. * Subjects having a Sigma RP PS TKA will experience continuous axial rotation in deep flexion. * Subjects having a Sigma RP PS TKA will experience optimal distribution of tibio-femoral and cam/post contact forces over a broad area on the post. * Subjects having a Sigma RP PS TKA will experience a smooth transition of the cam on the post, not an abrupt slide as seen with fixed bearing PS TKA. * The use of the sound sensors will detect cam/post contact mechanics under in vivo conditions.

Registry
clinicaltrials.gov
Start Date
April 2012
End Date
November 2012
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
The University of Tennessee, Knoxville
Responsible Party
Principal Investigator
Principal Investigator

Richard Komistek

Principal Investigator

The University of Tennessee, Knoxville

Eligibility Criteria

Inclusion Criteria

  • At least six months post-operative
  • Between 40-85 years of age
  • Have a body weight of less than 250 lbs.
  • Judged clinically successful with a AKS greater than 90
  • Have the DePuy Sigma mobile bearing TKA
  • Good-to-excellent post-operative passive flexion
  • Must be willing to sign the IC and HIPAA forms.

Exclusion Criteria

  • Pregnant females
  • Those not willing to sign the IC and HIPAA forms

Outcomes

Primary Outcomes

Range of Motion During Flexion of Deep Knee Bend Activity

Time Frame: 10 yrs post-operative

In Vivo Linear Knee Kinematics From Fluoroscopy Evaluation During Deep Knee Bend Activity

Time Frame: 10 yrs post-operative

The values that were reported indicate the motion of the contact point from full extension to patient's maximum flexion. Throughout flexion, if the point translated forward (anteriorly) atop the tibial tray, the number was reported as positive. If the point traveled backwards (posteriorly) atop the tibial tray, the number was reported as negative.

Femoral Axial Rotation With Respect to the Tibia During Deep Knee Bend Activity

Time Frame: 10 yrs post-operative

Secondary Outcomes

  • In Vivo Knee Force Values From Fluoroscopy Evaluation During Deep Knee Bend Activity(10 yrs post-operative)
  • Condyle Contact Stress at Maximum Flexion During Deep Knee Bend Activity(10 yrs post-operative)
  • Condyle Contact Area at Maximum Flexion During Deep Knee Bend Activity(10 yrs post-operative)

Study Sites (3)

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